Cat. #152694
Anti-DNA Ligase 1 [7A12]
Cat. #: 152694
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 1-2 weeks
Target: DNA Ligase 1
Class: Monoclonal
Application: WB ; ELISA ; IHC ; IP ; WB
Reactivity: Bovine ; Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Julian Gannon
Institute: Cancer Research UK, London Research Institute: Lincoln's Inn Fields
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-DNA Ligase 1 [7A12]
- Research fields: Genetics
- Clone: 7A12
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 125 kDa
- Strain: Balb/c
- Reactivity: Bovine ; Human
- Host: Mouse
- Application: WB ; ELISA ; IHC ; IP ; WB
- Description: DNA ligase 1 is involved in DNA replication and the nucleotide excision repair pathway.
- Immunogen: Bovine DNA Ligase I
- Isotype: IgG1
- Myeloma used: Sp2/0-Ag14
Target Details
- Target: DNA Ligase 1
- Molecular weight: 125 kDa
- Target background: DNA ligase 1 is involved in DNA replication and the nucleotide excision repair pathway.
Applications
- Application: WB ; ELISA ; IHC ; IP ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Liang et al. 2008. Nucleic Acids Res. 36(10):3297-310. PMID: 18440984.
- Human DNA ligases I and III, but not ligase IV, are required for microhomology-mediated end joining of DNA double-strand breaks.
- Prigent et al. 1994. Mol Cell Biol. 14(1):310-7. PMID: 8264597.
- Aberrant DNA repair and DNA replication due to an inherited enzymatic defect in human DNA ligase I.
