Cat. #153494
Anti-Cytokeratin 2e [LHK2E]
Cat. #: 153494
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 10-12 weeks
Target: Keratin K2e
Class: Monoclonal
Application: IHC ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Ahmad Waseem
Institute: Queen Mary University of London
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-Cytokeratin 2e [LHK2E]
- Alternate name: CK 2e antibody, Cytokeratin-2e antibody, Epithelial keratin-2e antibody, K2e antibody, Keratin type II cytoskeletal 2 epidermal antibody, Keratin-2 epidermis antibody, KRT2 antibody, KRT2A antibody, KRT2E antibody, Type-II keratin Kb2 antibody
- Research fields: Cancer;Cell signaling and signal transduction
- Clone: LHK2E
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Strain: Balb/c
- Reactivity: Human
- Host: Mouse
- Application: IHC ; WB
- Description: The cytoskeleton in keratinocytes is a complex of highly homologous structural proteins derived from two families of type I and type II polypeptides. Keratin K2e is a type II polypeptide that is expressed in epidermis late in differentiation. K2e expression in skin is sensitive to keratinocyte activation but its up-regulation in oral lesions is a reflection of the degree of orthokeratinization.
- Immunogen: C terminus of the K2e polypeptide (synthetic peptide NH2-GEAFGSSVTFSFR-COOH)
- Isotype: IgM
- Myeloma used: Sp2/0-Ag14
Target Details
- Target: Keratin K2e
- Target background: The cytoskeleton in keratinocytes is a complex of highly homologous structural proteins derived from two families of type I and type II polypeptides. Keratin K2e is a type II polypeptide that is expressed in epidermis late in differentiation. K2e expression in skin is sensitive to keratinocyte activation but its up-regulation in oral lesions is a reflection of the degree of orthokeratinization.
Applications
- Application: IHC ; WB
Handling
- Format: Liquid
- Unit size: 100 ug
- Shipping conditions: Dry ice
References
- Bloor et al. 2003. Am J Pathol. 162(3):963-75. PMID: 12598329.
- Expression of keratin K2e in cutaneous and oral lesions: association with keratinocyte activation, proliferation, and keratinization.
