#151068

Anti-cMyc [9E11]

Cat. #151068

Anti-cMyc [9E11]

Cat. #: 151068

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 3-4 weeks

Target: cMyc

Class: Monoclonal

Application: ChIP ; FACS ; IHC ; IP ; WB

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Gerard Evan

Institute: Cancer Research UK, London Research Institute: Lincoln's Inn Fields

Tool Details
Target Details
Applications
Handling
Related Tools
References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: Anti-cMyc [9E11]
  • Cancer: Gynaecologic cancer;Digestive / Gastrointestinal cancer;Breast cancer;Lung cancer
  • Cancers detailed: Cervix;Colorectal;Breast cancer;Lung;Stomach;Broadly Applicable
  • Research fields: Cancer;Cell biology;Genetics;Stem cell biology
  • Clone: Array
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Strain: Balb/c
  • Reactivity: Human
  • Host: Mouse
  • Application: ChIP ; FACS ; IHC ; IP ; WB
  • Description: The c-Myc and N-Myc oncogenes are members of the Myc family of transcription factors that regulate cell proliferation and apoptosis. c-Myc is expressed in proliferating tissues and increased c-Myc expression is found in many cancers. N-Myc is amplified in a proportion of neuroblastoma patients.
  • Immunogen: Residues 408-420. AEEQKLISEEDL.
  • Immunogen uniprot id: P01106
  • Isotype: IgG2a
  • Myeloma used: Sp2/0-Ag14

Target Details

  • Target: cMyc
  • Target background: The c-Myc and N-Myc oncogenes are members of the Myc family of transcription factors that regulate cell proliferation and apoptosis. c-Myc is expressed in proliferating tissues and increased c-Myc expression is found in many cancers. N-Myc is amplified in a proportion of neuroblastoma patients.

Applications

  • Application: ChIP ; FACS ; IHC ; IP ; WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C

Related Tools

  • Related tools: Anti-cMyc [9E10]

References

  • Mittal et al. 2013. PLoS One. 8(8):e70352. PMID: 23936412.
  • Role of CTLA4 in the proliferation and survival of chronic lymphocytic leukemia.
  • Mirzaei et al. 2013. Proc Natl Acad Sci U S A. 110(9):3645-50. PMID: 23388641.
  • Systematic measurement of transcription factor-DNA interactions by targeted mass spectrometry identifies candidate gene regulatory proteins.
  • Keyhanfar et al. 2007. Biochem J. 401(1):269-77. PMID: 16981855.
  • Precise mapping of an IGF-I-binding site on the IGF-1R.
  • Halm...