Cat. #158414
Anti-cancer inhibitor of protein phosphotase 2A [4A9-1A2]
Cat. #: 158414
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 10-12 weeks
Target: Cancerous Inhibitor of Protein Phosphatase 2A
Class: Monoclonal
Application: WB ; IP
Reactivity: Human ; Rat ; Mouse
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Edward Chan
Institute: University of Florida Research Foundation
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-cancer inhibitor of protein phosphotase 2A [4A9-1A2]
- Alternate name: CIP2A
- Research fields: Cancer;Cell signaling and signal transduction
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Reactivity: Human ; Rat ; Mouse
- Host: Mouse
- Application: WB ; IP
- Description: CIP2A is an oncoprotein that inhibits PP2A tumor suppressor activity in human malignancies by preventing degredation of c-Myc and regulates the phosphorylation of many oncoproteins. CIP2A is required for malignant cellular growth and tumor formation and is overexpressed in several human cancers: head and neck squamous cell carcimona, colon cancer, gastric cancer, breast cancer, prostate cancer, and lung caner.
- Immunogen: MAb were generated using the C-terminal third of the recombinant human protein as antigen
- Isotype: IgG1 kappa
Target Details
- Target: Cancerous Inhibitor of Protein Phosphatase 2A
- Target background: CIP2A is an oncoprotein that inhibits PP2A tumor suppressor activity in human malignancies by preventing degredation of c-Myc and regulates the phosphorylation of many oncoproteins. CIP2A is required for malignant cellular growth and tumor formation and is overexpressed in several human cancers: head and neck squamous cell carcimona, colon cancer, gastric cancer, breast cancer, prostate cancer, and lung caner.
Applications
- Application: WB ; IP
Handling
- Format: Liquid
- Unit size: 100 ug
- Shipping conditions: Shipping at 4° C
References
- Wei et al. 2019. Oncol Lett. 17(3):3211-3218. PMID: 30867751.
