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#153779

Anti-Centrobin [6D4F4]

Cat. #153779

Anti-Centrobin [6D4F4]

Cat. #: 153779

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 3-4 weeks

Target: Centrobin, UniProt ID:Q8N137

Class: Monoclonal

Application: IHC ; IF ; IP ; WB

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Ciaran Morrison

Institute: National University of Ireland, Galway; Centre For Chromosome Biology

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: Anti-Centrobin [6D4F4]
  • Alternate name: Centrosomal BRCA2-interacting protein, LYST-interacting protein 8
  • Research fields: Cancer;Cell biology
  • Clone: [6D4F4]
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Molecular weight: 100 kDa (runs at c. 110 kDa on WB)
  • Reactivity: Human
  • Host: Mouse
  • Application: IHC ; IF ; IP ; WB
  • Description: Centrobin is a centriole-associated protein that asymmetrically localises to the daughter centriole, and is required for centriole duplication and cytokinesis.
  • Immunogen: Recombinant human centrobin amino acids 113-361 (bacterially expressed from pGEX4T as a GST fusion, then thrombin-cleaved and purified).
  • Isotype: IgG1 kappa
  • Myeloma used: Sp2/0-Ag14
  • Recommended controls: IF and WB: hTERT-RPE1, IF only: Jurkat, U2OS, SHSY5Y, DT40 (chicken)

Target Details

  • Target: Centrobin, UniProt ID:Q8N137
  • Molecular weight: 100 kDa (runs at c. 110 kDa on WB)
  • Tissue cell line specificity: IF and WB: hTERT-RPE1, IF only: Jurkat, U2OS, SHSY5Y, DT40 (chicken)
  • Target background: Centrobin is a centriole-associated protein that asymmetrically localises to the daughter centriole, and is required for centriole duplication and cytokinesis.

Applications

  • Application: IHC ; IF ; IP ; WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Dry ice

References

  • Ogungbenro et al. 2018. J Cell Biol. 217(4):1205-1215. PMID: 29440264.
  • Centrobin controls primary ciliogenesis in vertebrates.

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