Anti-CD68 [Y1/82A] mAb

Cat. #151370

Anti-CD68 [Y1/82A] mAb

Cat. #: 151370

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 3-4 weeks

Target: CD68

Class: Monoclonal

Application: FACS ; IHC ; IF ; WB

Reactivity: Human

Host: Mouse


This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.


Inventor: Jacqueline Cordell

Institute: University of Oxford

Tool Details
Target Details

Tool Details


  • Name: Anti-CD68 [Y1/82A] mAb
  • Alternate name: CD68 Molecule; CD68 Antigen; Macrophage Antigen CD68; GP11; Scavenger Receptor Class D; Member; Scavenger Receptor Class D; SCARD1; LAMP4
  • Clone: Y1/82A
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Application: FACS ; IHC ; IF ; WB
  • Description: Monoclonal antibody directed against CD68, which can aid diagnosis of monocytic leukaemia's and histiocytic neoplasms and help identify macrophages in tissues from various inflammatory and neoplastic disease states.
  • Immunogen: Lysosomal contents of lung macrophages
  • Immunogen uniprot id: P34810
  • Isotype: IgG2a
  • Myeloma used: P3/NS1/1-Ag4.1

Target Details

  • Target: CD68
  • Target background: CD68 is a 110 kD glycoprotein, also known as macrosialin, belonging to the sialomucin family. It is closely related to the family of acidic, highly glycosylated lysosomal-associated membrane proteins (LAMPs). CD68 is predominately expressed in cytoplasmic granules of monocytes/macrophages, dendritic cells, and granulocytes. It is one of the useful myeloid cell markers. Further studies have shown that CD68 is also expressed by a subset of hematopoietic progenitors, ?/d T cells, NK cells, LAK cells, subset of B cells, fibroblasts, and endothelial cells. The biological function of CD68 is still unknown. Anti-CD68 (Y1/82A) reacted with peripheral blood and bone marrow monocytes and resident macrophages in all tissues tested. Anti-CD68 did not react with other cell types, apart from some osteoclasts and megakaryocytes. This antibody was shown to be useful in characterising monocytic leukaemia's, histiocytic neoplasms and detecting macrophages in disease.


  • Application: FACS ; IHC ; IF ; WB


  • Format: Liquid
  • Concentration: 1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: Store at -20° C frozen. Avoid repeated freeze / thaw cycles
  • Shipping conditions: Shipping at 4° C


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