CD68 is a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. CD68 is a member of a family of hematopoietic mucin-like molecules that includes leukosialin/CD43 and stem cell antigen CD34.
| Inventor | Institute |
|---|---|
| Jacqueline Cordell | University of Oxford |
| Cat. #: | 151793 |
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| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cell biology;Immunology;Stem cell biology |
| Application: | WB |
| Target: | CD68 |
| Reactivity: | Human |
| Clone: | Y-2/131/47 |
| Host: | Mouse |
| Class: | Monoclonal |
| Alternate name: | CD68 Molecule; CD68 Antigen; Macrophage Antigen CD68; GP11; Scavenger Receptor Class D; Member; Scavenger Receptor Class D; SCARD1; LAMP4 |
|---|---|
| Product description: | CD68 is a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. CD68 is a member of a family of hematopoietic mucin-like molecules that includes leukosialin/CD43 and stem cell antigen CD34. |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Immunogen: | Phytohaemagglutinin-activated peripheral blood mononuclear cells |
| Myeloma used: | P3/NS1/1-Ag4.1 |
| Target background: | CD68 is a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. CD68 is a member of a family of hematopoietic mucin-like molecules that includes leukosialin/CD43 and stem cell antigen CD34. |
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| Format: | Liquid |
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| Concentration: | 1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Doussis et al. 1993. J Clin Pathol. 46(4):334-6. PMID: 7684403. CD68 reactivity of non-macrophage derived tumours in cytological specimens. Pulford et al. 1990. Int Immunol. 2(10):973-80. PMID: 2078523. Distribution of the CD68 macrophage/myeloid associated antigen. Micklem et al. 1989. Br J Haematol. 73(1):6-11. PMID: 2803980. A human macrophage-associated antigen (CD68) detected by six different monoclonal antibodies. Pulford et al. 1989. J Clin Pathol. 42(4):414-21. PMID: 2654191. KP1: a new monoclonal antibody that detects a monocyte/macrophage associated antigen in routinely processed tissue sections. |
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