#155246

Anti-CD3 [500.A2]

Cat. #155246

Anti-CD3 [500.A2]

Cat. #: 155246

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 3-4 weeks

Target: CD3

Class: Monoclonal

Host: Hamster

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Institute: Yale University

Tool Details
Target Details
Handling
References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: Anti-CD3 [500.A2]
  • Cancer: Head and neck cancer
  • Cancers detailed: Nasopharyngeal
  • Research fields: Immunology
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Purpose: Marker
  • Conjugation: Unconjugated
  • Host: Hamster
  • Description: Monoclonal antibody capable of activating T cells and cloned T cell lines. Background and Research Application The CD3 complex, composed of four distinct CD3 polypeptide chains (CD3?, CD3? and 2X CD3?), associates with the T cell antigen receptor (TCR. CD3 is a member of the immunoglobulin superfamily, involved in antigen recognition, T lymphocyte activation and signal transduction. CD3 may play a role in TCR-induced growth arrest, cell survival and proliferation. The CD3 antigen is present ...
  • Immunogen: 25-kDa e chain of the T-cell receptor-associated CD3 complex
  • Immunogen uniprot id: A0A3Q0CNZ4
  • Isotype: IgG

Target Details

  • Target: CD3
  • Target background: Monoclonal antibody capable of activating T cells and cloned T cell lines. Background and Research Application The CD3 complex, composed of four distinct CD3 polypeptide chains (CD3?, CD3d and 2X CD3), associates with the T cell antigen receptor (TCR. CD3 is a member of the immunoglobulin superfamily, involved in antigen recognition, T lymphocyte activation and signal transduction. CD3 may play a role in TCR-induced growth arrest, cell survival and proliferation. The CD3 antigen is p...

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: Store at -20° C frozen. Avoid repeated freeze / thaw cycles
  • Shipping conditions: Shipping at 4° C

References

  • Chen et al. 2019. JCI Insight. 4(22):. PMID: 31723059.
  • Trittel et al. 2019. Sci Rep. 9(1):16362. PMID: 31704965.
  • Czarnewski et al. 2019. Nat Commun. 10(1):2892. PMID: 31253778.
  • Zwick et al. 2019. Front Immunol. 10:222. PMID: 30809231.
  • Shahbaz et al. 2018. PLoS Biol. 16(12):e2006649. PMID: 30550561.
  • Maj et al. 2017. Nat Immunol. 18(12):1332-1341. PMID: 29083399.
  • Long et al. 2016. Genes (Basel). 8(1):. PMID: 28035981.
  • Portoles et al. 1989. J Immunol. 142(12):4169-75. PMID: 2470817.