Cat. #151788
Anti-CD19 [LC-1/32/A10]
Cat. #: 151788
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 10-12 weeks
Target: CD19
Class: Monoclonal
Application: IHC ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Jacqueline Cordell
Institute: University of Oxford
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-CD19 [LC-1/32/A10]
- Alternate name: CD19 Molecule; B-Lymphocyte Surface Antigen B4; T-Cell Surface Antigen Leu-12; Differentiation Antigen CD19; CD19 Antigen; CVID3; B4
- Research fields: Cancer;Cell signaling and signal transduction;Immunology;Stem cell biology
- Clone: LC-1/32/A10
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Reactivity: Human
- Host: Mouse
- Application: IHC ; WB
- Description: CD19 is a cell surface molecule expressed on B lymphocytes and follicular dendritic cells. It is expressed by most pre-B cells and by the majority of non-T-cell acute lymphocytic leukaemias and B-cell type chronic lymphocytic leukaemias. CD19 assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation.
- Immunogen: A synthetic peptide, corresponding to the C-Terminus of CD19.
- Isotype: IgG1 kappa
- Myeloma used: NS0
- Recommended controls: Any human lymphoid tissue or Ramos cell line for CD19 positive and Jurkat for CD19 negative.
Target Details
- Target: CD19
- Tissue cell line specificity: Any human lymphoid tissue or Ramos cell line for CD19 positive and Jurkat for CD19 negative.
- Target background: CD19 is a cell surface molecule expressed on B lymphocytes and follicular dendritic cells. It is expressed by most pre-B cells and by the majority of non-T-cell acute lymphocytic leukaemias and B-cell type chronic lymphocytic leukaemias. CD19 assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation.
Applications
- Application: IHC ; WB
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -20° C
- Shipping conditions: Dry ice
References
- Carter et al. 1992. Science. 256(5053):105-7. PMID: 1373518.
- CD19: lowering the threshold for antigen receptor stimulation of B lymphocytes.
- Tedder et al. 1989. J Immunol. 143(2):712-7. PMID: 2472450.
- Isolation of cDNAs encoding the CD19 antigen of human and mouse B lymphocytes. A new member of the immunoglobulin superfamily.
