Contributes to the regulation of cell cycle progression. Required for normal mitosis. Associates with the centrosome and the spindle microtubules during mitosis and functions in centrosome maturation, spindle assembly, maintenance of spindle bipolarity, centrosome separation and mitotic checkpoint control.
| Institute |
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| University of Cambridge |
| Cat. #: | 151798 |
|---|---|
| Unit size: | 100 ug |
| Research Fields: | Cell biology |
| Application: | WB |
| Target: | Drosophila Aurora A |
| Reactivity: | Drosophila |
| Clone: | Aur A |
| Host: | Rabbit |
| Class: | Polyclonal |
| Product description: | Contributes to the regulation of cell cycle progression. Required for normal mitosis. Associates with the centrosome and the spindle microtubules during mitosis and functions in centrosome maturation, spindle assembly, maintenance of spindle bipolarity, centrosome separation and mitotic checkpoint control. |
|---|---|
| Conjugation: | Unconjugated |
| Isotype: | Isotype: inconclusive – negative on both kits (CRT IgG1) |
| Immunogen: | Maltose-binding protein (MBP) fusion proteins |
| Immunogen Uniprot ID: | N/A |
| Target background: | Contributes to the regulation of cell cycle progression. Required for normal mitosis. Associates with the centrosome and the spindle microtubules during mitosis and functions in centrosome maturation, spindle assembly, maintenance of spindle bipolarity, centrosome separation and mitotic checkpoint control. |
|---|
| Format: | Liquid |
|---|---|
| Shipping conditions: | Dry ice |
| References: |
Barros et al. 2005. J Cell Biol. 170(7):1039-46. PMID: 16186253. Aurora A activates D-TACC-Msps complexes exclusively at centrosomes to stabilize centrosomal microtubules. |
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