#151274

Anti-AP2b [AP2bbeta 1F3/8]

Cat. #151274

Anti-AP2b [AP2bbeta 1F3/8]

Cat. #: 151274

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 1-2 weeks

Target: Activating Protein 2 (AP-2) beta

Class: Monoclonal

Application: ELISA ; IHC ; WB

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Helen Hurst

Institute: Queen Mary Innovation Ltd

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: Anti-AP2b [AP2bbeta 1F3/8]
  • Research fields: Cancer;Genetics;Tissue-specific biology
  • Clone: AP2b? 1F3/8
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Molecular weight: 50 kDa
  • Strain: Balb/c
  • Reactivity: Human
  • Host: Mouse
  • Application: ELISA ; IHC ; WB
  • Description: AP-2 is a family of developmentally regulated transcription factors which also play a role in breast cancer and melanoma. AP-2?Ÿ may be important in cardiac and kidney development. The AP-2 transcription factors form the OB2 complex that has been shown to up-regulate c-erb-B2 transcription.
  • Immunogen: Truncated AP-2? protein prepared from bacteria
  • Isotype: IgG2a
  • Myeloma used: Sp2/0-Ag14
  • Recommended controls: Human breast cancer line MDA MB 453

Target Details

  • Target: Activating Protein 2 (AP-2) beta
  • Molecular weight: 50 kDa
  • Tissue cell line specificity: Human breast cancer line MDA MB 453
  • Target background: AP-2 is a family of developmentally regulated transcription factors which also play a role in breast cancer and melanoma. AP-2? may be important in cardiac and kidney development. The AP-2 transcription factors form the OB2 complex that has been shown to up-regulate c-erb-B2 transcription.

Applications

  • Application: ELISA ; IHC ; WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C

References

  • Ebauer et al. 2007. Oncogene. 26(51):7267-81. PMID: 17525748.
  • Comparative expression profiling identifies an in vivo target gene signature with TFAP2B as a mediator of the survival function of PAX3/FKHR.