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#151336

Anti-Alkaline phosphatase [AP-7/6/7]

Cat. #151336

Anti-Alkaline phosphatase [AP-7/6/7]

Cat. #: 151336

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 3-4 weeks

Target: Alkaline phosphatase

Class: Monoclonal

Application: IHC ; IF

Reactivity: Bovine

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Jacqueline Cordell

Institute: University of Oxford

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: Anti-Alkaline phosphatase [AP-7/6/7]
  • Research fields: Cancer;Cell biology
  • Clone: AP-7/6/7
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Reactivity: Bovine
  • Host: Mouse
  • Application: IHC ; IF
  • Description: Alkaline phosphatases are phosphodiesterases which remove phosphate groups from the 5' end of DNA, RNA and proteins at high pH. The placental-specific isozyme of Alkaline Phosphatase (PLAP) is found in trophoblast cells of normal human mature placenta, seminomas of testis and ovarian carcinomas. Detection of alkaline phosphatase in serum is a marker for ovarian and testicular cancer.
  • Immunogen: Calf intestinal alkaline phosphatase
  • Isotype: IgG1
  • Myeloma used: P3/NS1/1-Ag4.1

Target Details

  • Target: Alkaline phosphatase
  • Target background: Alkaline phosphatases are phosphodiesterases which remove phosphate groups from the 5' end of DNA, RNA and proteins at high pH. The placental-specific isozyme of Alkaline Phosphatase (PLAP) is found in trophoblast cells of normal human mature placenta, seminomas of testis and ovarian carcinomas. Detection of alkaline phosphatase in serum is a marker for ovarian and testicular cancer.

Applications

  • Application: IHC ; IF

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -80° C
  • Shipping conditions: Dry ice

References

  • Cordell et al. 1984. J Histochem Cytochem. 32(2):219-29. PMID: 6198355.
  • Immunoenzymatic labeling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal anti-alkaline phosphatase (APAAP complexes).

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