ADAM15 is an active metalloproteinase with gelatinolytic and collagenolytic activity which plays a role in the wound healing process. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules.
| Inventor | Institute |
|---|---|
| Carl Blobel | Hospital for Special Surgery |
| Cat. #: | 152541 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cancer;Cell biology;Cell signaling and signal transduction |
| Application: | WB |
| Target: | ADAM15 |
| Reactivity: | Mouse |
| Clone: | 15MODIS |
| Host: | Rabbit |
| Class: | Polyclonal |
| Product description: | ADAM15 is an active metalloproteinase with gelatinolytic and collagenolytic activity which plays a role in the wound healing process. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. |
|---|---|
| Conjugation: | Unconjugated |
| Molecular weight: | ~100 kDa |
| Immunogen: | Disintegrin domain, cysteine-rich region and an epidermal growth factor repeat from murine ADAM15 |
| Target background: | ADAM15 is an active metalloproteinase with gelatinolytic and collagenolytic activity which plays a role in the wound healing process. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 0.9-1.1 mg/ml |
| Storage buffer: | Whole serum |
| Storage conditions: | -20° C |
| Shipping conditions: | Dry ice |
| References: |
Horiuchi et al. 2003. Mol Cell Biol. 23(16):5614-24. PMID: 12897135. KrĤtzschmar et al. 1996. J Biol Chem. 271(9):4593-6. PMID: 8617717. Lum et al. 1998. J Biol Chem. 273(40):26236-47. PMID: 9748307. Maretzky et al. 2009. Biochem J. 420(1):105-13. PMID: 19207106. Maretzky et al. 2009. Cancer Res. 69(11):4573-6. PMID: 19487280. |
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