Cat. #157674
P815.Trh4 cell line
Cat. #: 157674
Sub-type: Continuous
Unit size: 1x10^6 cells / vial
Availability: 8-10 weeks
Organism: Mouse
Tissue: Bone Marrow
Disease: Cancer
Model: Tumour line
£575.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Thorbald Van Hall
Institute: Leiden University and Leiden University Medical Center; Stichting Oncode Institute
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: P815.Trh4 cell line
- Cancers detailed: Mouse mast cell neoplasm
- Research fields: Cancer
- Tool sub type: Continuous
- Parental cell: P815
- Organism: Mouse
- Tissue: Bone Marrow
- Disease: Cancer
- Model: Tumour line
- Description: This cell line provides a model to help to understand T-cell recognition through Trh4 expression. ER-resident ceramide synthase Trh4 is a prototypic example of a neo-antigen selectively presented by cells through various pathways. The P815 cell line has been made to over-express Trh4 and can be utilised to understand this peptide presentation process.
- Production details: Retroviral transduction of the mouse Trh4 gene in an IRES-GFP construct
- Biosafety level: 1
- Cellosaurus id: CVCL_2154
Target Details
- Target: Trh4
Handling
- Format: Frozen
- Unit size: 1x10^6 cells / vial
- Shipping conditions: Dry ice
- Storage conditions: Liquid Nitrogen
- Mycoplasma free: Yes
References
- Oliveira et al. 2011. Eur J Immunol. 41(11):3114-24. PMID: 21898382.
