#154340

pTRE/SP M87 S245X vector

Cat. #154340

pTRE/SP M87 S245X vector

Cat. #: 154340

Sub-type: pTRE-Tight

Availability: Please enquire for quantities and pricing

Target: spastin

Bacterial Resistance: Ampicillin

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Institute: Drexel University

Tool Details
Target Details
References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Tool name: pTRE/SP M87 S245X vector
  • Research fields: Cell biology;Genetics;Neurobiology
  • Tool sub type: pTRE-Tight
  • Backbone size without insert: 2600
  • Bacterial resistance: Ampicillin
  • Description: Plasmids for the study of hereditary spastic paraplegia
  • Additional notes: Plasmids for the study of hereditary spastic paraplegia

Target Details

  • Target: spastin

References

  • Solowska et al. 2017. Mol Biol Cell. 28(13):1728-1737. PMID: 28495799.
  • Truncating mutations of SPAST associated with hereditary spastic paraplegia indicate greater accumulation and toxicity of the M1 isoform of spastin.