#156514

pFLAG-HBx vector

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Cat. #156514

pFLAG-HBx vector

Cat. #: 156514

Sub-type: pcDNA3.1

Availability: Please enquire for quantities and pricing

Target: HBx with FLAG tag at N-terminus

Bacterial Resistance: Ampicillin

Selectable Markers: Neomycin

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Michael Bouchard

Institute: Drexel University

Tool Details
Handling
Target Details
Application Details
References

Tool Details

*FOR RESEARCH USE ONLY

  • Tool name: pFLAG-HBx vector
  • Alternate name: nonstructural protein X, protein X, peptide X, pX
  • Research fields: Cancer;Microbiology
  • Tool sub type: pcDNA3.1
  • Backbone size without insert: 5428
  • Bacterial resistance: Ampicillin
  • Selectable markers: Neomycin
  • Description: This vector can be used to express hepatitis B virus HBx protein in a variety of primary and cancer cells. The addition of the FLAG-epitope tag allows for detection in western and immunofluorescent cell-based studies and provides better detection ability than can currently be achieved with commercially available anti-HBx antibodies.
  • Application: p

Handling

  • Shipping conditions: Dry Ice

Target Details

  • Target: HBx with FLAG tag at N-terminus

Application Details

  • Application: p
  • Application notes: Multi-functional hepatitis B viral protein, non-structural protein X, that modulates mitochondrial function in host hepatocytes interfering with host anti-viral defenses, promoting viral transcription, and contributing to hepatocellular carcinoma development.

References

  • Clippinger et al. 2008. J Virol. 82(14):6798-811. PMID: 18448529.
  • McClain et al. 2007. J Virol. 81(21):12061-5. PMID: 17699583.