Glycated HSA Fluorecein Boronic Acid small molecule (tool compound)

Protein glycation, also known as non-enzymatic glycosylation, has been implicated in various disease states and is therefore an important biomarker for ageing and age-related chronic diseases such as diabetes, cardiovascular diseases, autoimmune diseases, cancer, and Alzheimer’s disease. However their analysis is challenging due to the complexity of the protein-carbohydrate adducts. Fluorescent boronic acids like these […]

Contributors

Inventor Institute
Marta P. Pereira Morais University of Bath
Cat. #: 154473
Research Fields: Neurobiology;Biochemistry;Immunology
Alternate name: AGEs
Product description: Protein glycation, also known as non-enzymatic glycosylation, has been implicated in various disease states and is therefore an important biomarker for ageing and age-related chronic diseases such as diabetes, cardiovascular diseases, autoimmune diseases, cancer, and Alzheimer's disease. However their analysis is challenging due to the complexity of the protein-carbohydrate adducts. Fluorescent boronic acids like these enable the detection and identification of individual glycated proteins in…
Additional notes: This small molecule has been used to identify glycated proteins in human serum, insect hemolymph, and mouse brain homogenates.
Primary target: Advanced Glycation Endproducts (AGE); specifically Glycated Human Serum Albumin (HSA). Also binds ApoA-I protein
Shipping conditions: Dry Ice
References:

Pereira Morais et al. 2013. Sci Rep. 3:1437. PMID: 23531746.

Related Tools for Small molecules

Cat. # Tool Name
151839 Antitumoral Phortress Small Molecule (Tool Compound) Key Info View Tool
152709 Dual DNA-PK/PI3K inhibitor KU-0060648 Small Molecule (Tool Compound) Key Info View Tool
152785 Mitochondrial Luminophore Small Molecule (Tool Compound) Key Info View Tool
152786 Nucleolar Luminophore Ag-1 Small Molecule (Tool Compound) Key Info View Tool
152789 Glucose-6-phosphate Dehydrogenase inhibitor G6PD Small Molecule (Collaborative Toolkit) Key Info View Tool

Tool enquiry

Please ensure you use your organisation email address rather than personal where possible, as this helps us locate your organisation in our system faster.

Please note we may take up to three days to respond to your enquiry.

CancerTools.org uses the contact information provided to respond to you about our research tools and service. For more information please review our privacy policy.