
Anti-MMP3 [1B4] Product
The enzyme is also thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation.
The enzyme is also thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation.
[…] and activate transcription but remain competent for transcriptional repression. Expression of Omomyc can induce rapid tumour regression in mouse models with little toxicity for normal tissues, acting as a suppressor […]
[…] involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumour growth and invasion. This protein functions as a modifier of endothelial cell migration and […]
[…] strictly controlling degradation of ECM. The MMPs and TIMPs have a significant role in facilitating tumour invasion and metastasis._x000D_ _x000D_ Expression of MMP9 has been identified in individual studies as […]
Binds to Interleukin 4 (IL-4) and blocks activity.
The antibody, NCRC37, is a pan-reactive, anti-colorectal tumour antibody and binds strongly to coloretal tumour cells and to post mortem cryopreserved tissues of brain, spleen, heat, lung, kidney, testes, oesophagus […]
The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1.
MMP1 cleaves collagens of types I, II, and III at one site in the helical domain. MMP1 also cleaves collagens of types VII and X. In case of HIV infection, interacts and cleaves the secreted viral Tat protein, leading to a decrease in neuronal Tat’s mediated neurotoxicity.
Monoclonal antibody which targets the critical ser186 residue for MDM2 function.
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