#151619

Anti-MMP2 [4D3]

Cat. #151619

Anti-MMP2 [4D3]

Cat. #: 151619

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 3-4 weeks

Target: Human matrix metalloproteinase 2 (MMP-2)

Class: Monoclonal

Application: ELISA ; IHC ; IF ; IP ; WB

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Ayham Alnabulsi

Institute: Vertebrate Antibodies Limited

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: Anti-MMP2 [4D3]
  • Research fields: Cancer;Cell biology;Genetics;Metabolism;Tissue-specific biology
  • Clone: 4D3
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Strain: Balb/c
  • Reactivity: Human
  • Host: Mouse
  • Application: ELISA ; IHC ; IF ; IP ; WB
  • Description: MMP2 degrades type IV collagen and plays an important role in menstrual break down, regulation of vascularization, angiogenesis, and inflammatory response. Mutations of MMP2 are associated with Torg-Winchester syndrome.
  • Immunogen: Ovalbumin-conjugated synthetic peptide; TSLGLPPDVQRVD
  • Isotype: IgG1
  • Myeloma used: P3X63Ag8.653
  • Recommended controls: IHC: formalin-fixed, paraffin-embedded lung containing intra-alveolar macrophageswestern blot: rhMMP-2, 400 ng per lane

Target Details

  • Target: Human matrix metalloproteinase 2 (MMP-2)
  • Tissue cell line specificity: IHC: formalin-fixed, paraffin-embedded lung containing intra-alveolar macrophageswestern blot: rhMMP-2, 400 ng per lane
  • Target background: MMP2 degrades type IV collagen and plays an important role in menstrual break down, regulation of vascularization, angiogenesis, and inflammatory response. Mutations of MMP2 are associated with Torg-Winchester syndrome.

Applications

  • Application: ELISA ; IHC ; IF ; IP ; WB

Handling

  • Format: Liquid
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -80° C
  • Shipping conditions: Shipping at 4° C

References

  • Jeffery et al. 2009. Histopathology. 54(7):820-8. PMID: 19635101.
  • The matrix metalloproteinase/tissue inhibitor of matrix metalloproteinase profile in colorectal polyp cancers.
  • Lyall et al. 2006. Clin Cancer Res. 12(4):1184-91. PMID: 16489072.
  • Profiling markers of prognosis in colorectal cancer.
  • Curran et al. 2004. Clin Cancer Res. 10(24):8229-34. PMID: 15623598.
  • Matrix metalloproteinase/tissue inhibitors of matrix metalloproteinase phenotype identifies poor prognosis colorectal cancers.
  • Murray et al. 1998. Gut. 43(6):791-7. PMID: 9824606.
  • Matrix metalloproteinases and their inhibitors in gastric cancer.
  • Murray et al. 1998. J Pathol. 185(3):256-61. PMID: 9771478.
  • Matrix metalloproteinase-1 is associated with poor prognosis in oesophageal cancer.