Anti-PD-L1 [29E.2A3] Product
Cancer Cell signaling and signal transduction Immunology
Anti-p53 [DO-12] Product
Anti-p53 DO-12 antibody recognises the human cellular tumour antigen p53, also known as p53 tumour suppressor protein or NY-CO-13. p53 is a 393 amino acid ~53kDa cytoplasmic/ nuclear protein upregulated […]
Anti-p53 [Pab 240] Product
Monoclonal antibody reacts specifically with mutated p53 at an epitope conserved across species and normally hidden within the protein structure in non-mutant forms.
Anti-p53 Pab 240 was created further understand the biochemical role of p53 in cancers and the precise effects of mutation.Anti-p53 (Pab 240) antibody recognises an evolutionary conserved epitope upon p53 hidden within the normal protein structure, however it does not bind to immunoprecipitated wild type p53. This antibody recognises an epitope which is structurally elusive when p53 is in a wildtype conformation but becomes accessible upon denaturation or through mutational conformations where point mutations within the TP53 gene alter the conformational structure of the protein.
Anti-p53 [Pab DO-1] Product
Anti p53 monoclonal antibody used to analyse and detect the most mutated gene in cancer’ p53 and its protein interactions, enabling identification of transformed cell lines.
Anti-MMP3 [1B4] Product
The enzyme is also thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation.
Anti-MMP9 [2C3] Product
[…] strictly controlling degradation of ECM. The MMPs and TIMPs have a significant role in facilitating tumour invasion and metastasis. Expression of MMP9 has been identified in individual studies as prognostic […]
Anti-FGF1 [V8P1G5*F2] Product
[…] involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumour growth and invasion. This protein functions as a modifier of endothelial cell migration and […]
Anti-Omomyc [21-1-3] Product
[…] and activate transcription but remain competent for transcriptional repression. Expression of Omomyc can induce rapid tumour regression in mouse models with little toxicity for normal tissues, acting as a suppressor […]
HGS1 cell line Product
Human tumours comprise a complex mixture of malignant cells, immune, and other stromal cells regulated by a dynamic network of soluble mediators and adhesion molecules. All of these components interact […]
HGS3 cell line Product
Human tumours comprise a complex mixture of malignant cells, immune, and other stromal cells regulated by a dynamic network of soluble mediators and adhesion molecules. All of these components interact […]
