Skip to main content

#152932

Villin-Cre Apcfl/+ KRasG12D/+ Mouse

Cat. #152932

Villin-Cre Apcfl/+ KRasG12D/+ Mouse

Cat. #: 152932

Sub-type: Mouse

Availability: 8-10 weeks

Disease: Cancer

Model: Conditional Knock-Out

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Owen Sansom

Institute: Cancer Research UK, Glasgow: The Beatson Institute

Tool Details
Handling
Target Details

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Tool name: Villin-Cre Apcfl/+ KRasG12D/+ Mouse
  • Alternate name: GTPase KRasK-Ras 2Ki-Rasc-K-rasc-Ki-ras
  • Cancer: Digestive / Gastrointestinal cancer
  • Cancers detailed: Colorectal
  • Research fields: Cancer;Genetics
  • Tool sub type: Mouse
  • Disease: Cancer
  • Model: Conditional Knock-Out
  • Conditional: Yes
  • Description: Oncogenic mutations in the K-ras gene occur in 50% of human colorectal cancers. However, the precise role that K-ras oncogenes play in tumor formation is still unclear. To address this issue, we have conditionally expressed an oncogenic K-rasD12 allele in the small intestine of adult mice either alone or in the context of Apc deficiency.

Handling

  • Shipping conditions: Embryo/Spermatoza- Dry Ice

Target Details

  • Target: KRasG12D

Tool enquiry

Please ensure you use your organisation email address rather than personal where possible, as this helps us locate your organisation in our system faster.

Please note we may take up to three days to respond to your enquiry.

CancerTools.org uses the contact information provided to respond to you about our research tools and service. For more information please review our privacy policy.