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#162172

TsixTAD-KO mouse

Cat. #162172

TsixTAD-KO mouse

Cat. #: 162172

Sub-type: Mouse

Availability: 3-4 weeks

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Edith HEARD; Rafael GALUPA; Fatima EL MARJOU; Colin JOUHANNEAU

Institute: Institut Curie

Primary Citation: Rafael Galupa et.al. 2020. Mol Cell. Jan 16;77(2):352-367.e8. PMID: 31759823.

Tool Details
Handling
References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Tool name: TsixTAD-KO mouse
  • Official nomenclature: B6D2Fn-Tsix-TADem2Heard/Curie
  • Research fields: Genetics
  • Tool sub type: Mouse
  • Crispr: Yes
  • Description: This line was generated in the context of studying the relationship between chromosome organisation and gene expression at the X-inactivation centre, the regulatory locus that triggers X-chromosome inactivation. It could also be used to investigate the functions of the genes that are lost within the ~245kb deletion, including the poorly characterised genes Nap1L2, Cdx4, Chic1 and Tsx, among others.
  • Zygosity: Homozygous
  • Strain: B6D2F1

Handling

  • Shipping conditions: Sperm / dry ice

References

  • Rafael Galupa et.al. 2020. Mol Cell. Jan 16
  • 77(2):352-367.e8. PMID: 31759823.

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