Cat. #160435
UM-UC-4 (Human adenocarcinoma lymph node metastasis) cell line
Cat. #: 160435
Unit size: 1x10^6 cells / vial
Organism: Human
Tissue: Bladder
Disease: Cancer
Model: Tumourigenic cell line
£575.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: H. Grossman ; Anita Sabichi
Institute: University of Michigan
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: UM-UC-4 (Human adenocarcinoma lymph node metastasis) cell line
- Alternate name: UM-UC-4; UMUC4; University of Michigan-Urothelial Carcinoma-4
- Cancer: Genitourinary cancer
- Cancers detailed: Human squamous cell carcinoma of the bladder
- Research fields: Cancer
- Organism: Human
- Tissue: Bladder
- Disease: Cancer
- Growth properties: Adherent
- Model: Tumourigenic cell line
- Description: UM-UC-4 is a patient-derived human urothelial carcinoma cell line obtained from the lymphatic metastases of bladder cancer in a female patient. The UM-UC panel of urothelial carcinoma is a diverse range of 11 patient derived cell lines developed by the university of Michigan that have been well-categorised in the literature. These cells were assessed for their susceptibility to adenoviral mediated gene delivery, tumour growth in nude mice and differences in genetic alterations.
Handling
- Format: Frozen
- Growth medium: Cells were grown in Dulbecco's modified Eagle's medium (DMEM) containing 10% heat inactivated Fetal Bovine Serum (FBS) and were supplemented with 1% penicillin and streptomycin at 37°C in 5% CO2 environment.
- Unit size: 1x10^6 cells / vial
- Shipping conditions: Dry ice
Related Tools
- Related tools: UM-UC-1 (Human bladder transitional cell carcinoma) cell line ; UM-UC-3 (Human bladder transitional cell carcinoma) cell line ; UM-UC-5 (Human squamous cell carcinoma of the bladder) cell line ; UM-UC-7 (Human transitional cell carcinoma of the bladder) cell line ; UM-UC-9 (Human transitional cell carcinoma of the bladder) cell line ; UM-UC-10 (Human transitional cell carcinoma of the bladder) cell line ; UM-UC-11 (Human transitional cell carcinoma of the bladder) cell line
References
- Grossman et al. 1986. J Urol. 136(5):953-9. PMID: 3761468
- Sabichi et al. 2006. J Urol. 175(3 Pt 1):1133-7. PMID: 16469639
- Earl et al. 2015. BMC Genomics. 16:403. PMID: 25997541
- Zuiverloon et al. 2018. Bladder Cancer. 4(2):169-83. PMID: 29732388
