ICP8 is the major DNA binding protein of herpes simplex virus type 1.
| Inventor | Institute |
|---|---|
| Diane Wilcock | Cancer Research UK, London Research Institute: Clare Hall Laboratories |
| Cat. #: | 151027 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Microbiology |
| Application: | WB ; IHC ; WB |
| Target: | Herpes Simplex Virus Infected cell protein 8 (HSV-ICP8) |
| Reactivity: | Virus |
| Clone: | 10A3 |
| Host: | Mouse |
| Class: | Monoclonal |
| Alternate name: | Fc Fragment Of IgG Receptor Ia; Fc Gamma Receptor Ia; Fc-Gamma RIA; IGFR1; FCRI; Fc Gamma Receptor; CD64 Antigen; FCGR1; CD64; FCG1 |
|---|---|
| Product description: | ICP8 is the major DNA binding protein of herpes simplex virus type 1. |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Immunogen: | ICP8 purified from U-35-VERO cells. |
| Immunogen Uniprot ID: | P12314 |
| Myeloma used: | Sp2/0-Ag14 |
| Target background: | ICP8 is the major DNA binding protein of herpes simplex virus type 1. |
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| Format: | Liquid |
|---|---|
| Concentration: | 1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Sagou et al. 2009. J Virol. 83(11):5773-83. PMID: 19297494. Regulation of the catalytic activity of herpes simplex virus 1 protein kinase Us3 by autophosphorylation and its role in pathogenesis. Glauser et al. 2007. J Virol. 81(9):4732-43. PMID: 17314170. Live covisualization of competing adeno-associated virus and herpes simplex virus type 1 DNA replication: molecular mechanisms of interaction. |
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