
Cat. #151031
Anti-RuvA [RuvA 12C6]
Cat. #: 151031
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-4 weeks
Target: Ruv A protein.
Class: Monoclonal
Application: ELISA ; IHC ; IP ; RIA ; WB
Reactivity: E.coli
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Stephen West
Institute: Cancer Research UK, London Research Institute: Clare Hall Laboratories
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-RuvA [RuvA 12C6]
- Research fields: Genetics
- Clone: RuvA 12C6
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 22 kDa
- Strain: Balb/c
- Reactivity: E.coli
- Host: Mouse
- Application: ELISA ; IHC ; IP ; RIA ; WB
- Description: During genetic recombination and post replication repair of DNA damage, RuvA and RuvB (a helicase) act in a complex to promote branch migration of Holliday junctions and RuvC (an endonuclease) cleaves Holliday junctions.
- Immunogen: Ruv A protein from E. Coli
- Isotype: IgG1
- Myeloma used: Sp2/0-Ag14
Target Details
- Target: Ruv A protein.
- Molecular weight: 22 kDa
- Target background: During genetic recombination and post replication repair of DNA damage, RuvA and RuvB (a helicase) act in a complex to promote branch migration of Holliday junctions and RuvC (an endonuclease) cleaves Holliday junctions.
Applications
- Application: ELISA ; IHC ; IP ; RIA ; WB
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Dry ice
References
- Davies et al. 1998. Curr Biol. 8(12):725-7. PMID: 9637927.
- Formation of RuvABC-Holliday junction complexes in vitro.
- Eggleston et al. 1997. Cell. 89(4):607-17. PMID: 9160752.
- In vitro reconstitution of the late steps of genetic recombination in E. coli.