LNCaP androgen-independent cell line

The cell line is a clonal population of LNCaP cells grown in steroid-depleted conditions for ~4 months. Cells adapted to growth conditions and are now routinely grown in media lacking testosterone

Contributors

Institute
Northern Institute For Cancer Research, Newcastle University
Cat. #: 154164
Tool sub type: Continuous
Unit size: 1×10^6 cells / vial
Cancer types: Genitourinary cancer
Research Fields: Cancer
Organism: Human
Model: Tumour line
Cancer Types In Detail: Human prostate adenocarcinoma
Product description: LNCaP cells are androgen-sensitive human prostate adenocarcinoma cells derived from the left supraclavicular lymph node metastasis from a 50-year-old Caucasian male in 1977. The androgen receptor (AR) in LNCaP cells harbours a T877A mutations which enables the anti-androgen flutamide to act as an agonist. This cell line is the most commonly used for prostate cancer research. The cell line is a clonal population of LNCaP cells grown in steroid-depleted conditions for ~4 months. Cells adapted to growth conditions and are now routinely grown in media lacking testosterone
Conditional: No
Production details: LNCaP cells grown in steroid-depleted conditions for ~4 months
Parental cell line: LNCaP
disease: Cancer
Format: Frozen
Shipping conditions: Dry ice
Growth medium: RPMI-1640 + 10% charcoal-stripped FBS

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