#154164

LNCaP androgen-independent cell line

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Cat. #154164

LNCaP androgen-independent cell line

Cat. #: 154164

Sub-type: Continuous

Unit size: 1x10^6 cells / vial

Organism: Human

Disease: Cancer

Model: Tumour line

£575.00

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Contributor

Institute: Northern Institute For Cancer Research, Newcastle University

Tool Details
Handling

Tool Details

*FOR RESEARCH USE ONLY

  • Name: LNCaP androgen-independent cell line
  • Cancer: Genitourinary cancer
  • Cancers detailed: Human prostate adenocarcinoma
  • Research fields: Cancer
  • Tool sub type: Continuous
  • Parental cell: LNCaP
  • Organism: Human
  • Disease: Cancer
  • Model: Tumour line
  • Conditional: No
  • Description: LNCaP cells are androgen-sensitive human prostate adenocarcinoma cells derived from the left supraclavicular lymph node metastasis from a 50-year-old Caucasian male in 1977. The androgen receptor (AR) in LNCaP cells harbours a T877A mutations which enables the anti-androgen flutamide to act as an agonist. This cell line is the most commonly used for prostate cancer research. The cell line is a clonal population of LNCaP cells grown in steroid-depleted conditions for ~4 months. Cells adapted to growth conditions and are now routinely grown in media lacking testosterone
  • Production details: LNCaP cells grown in steroid-depleted conditions for ~4 months

Handling

  • Format: Frozen
  • Growth medium: RPMI-1640 + 10% FBS
  • Unit size: 1x10^6 cells / vial
  • Shipping conditions: Dry ice