Cat. #154230
HtrA3 (Clone 2C4)
Cat. #: 154230
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 10-12 weeks
Target: Human HtrA3 (high temperature requirement factor A)
Class: Monoclonal
Application: WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Institute: Hudson Institute Of Medical Research
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: HtrA3 (Clone 2C4)
- Alternate name: HtrA3
- Research fields: Tissue-specific biology
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 48 kDa (46.9 kDa plus 1 kDa for the His tag)
- Strain: Balb/c
- Reactivity: Human
- Host: Mouse
- Application: WB
- Description: Potential marker for preeclampsia. Detection of endogenous HtrA3 proteins in human serum HtrA3 are oligomeric serine proteases involved in protein quality control , regulate signal transduction in cell growth, apoptosis, inflammation in cancer, arthritis, neurodegenerative and neuromuscuclar disorders, age-related macular degeneration, pregnancy-specific disease preecampsia
- Immunogen: synthetic peptide TIKIHPKKKL (corresponding to residues 230-239 in both HtrA3-L and HtrA3-S
- Immunogen uniprot id: P83110, HTRA3_HUMAN
- Myeloma used: Sp2/0-Ag14
Target Details
- Target: Human HtrA3 (high temperature requirement factor A)
- Molecular weight: 48 kDa (46.9 kDa plus 1 kDa for the His tag)
- Target background: Potential marker for preeclampsia. Detection of endogenous HtrA3 proteins in human serum HtrA3 are oligomeric serine proteases involved in protein quality control , regulate signal transduction in cell growth, apoptosis, inflammation in cancer, arthritis, neurodegenerative and neuromuscuclar disorders, age-related macular degeneration, pregnancy-specific disease preecampsia
Applications
- Application: WB
Handling
- Format: Liquid
- Unit size: 100 ug
- Shipping conditions: Dry ice
Related Tools
- Related tools: HtrA3 Monoclonal Antibody (Clone 6G6) ; HtrA3 Monoclonal Antibody (Clone 9C9) ; HtrA3 Monoclonal Antibody (Clone 3E6) ; HtrA3 Monoclonal Antibody (Clone 10H10)
References
- 25248123
- 27932697
- HtrA3 as an early marker for preeclampsia: specific monoclonal antibodies and sensitive high-throughput assays for serum screening.
- Dynon et al. 2012. PLoS One. 7(9):e45956. PMID: 23049902.
