Cat. #151514
Anti-Zebrafish gut secretory cell epitopes [FIS 6G5/1]
Cat. #: 151514
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 1-2 weeks
Target: Zebrafish gut secretory cell epitopes
Class: Monoclonal
Application: ELISA ; IHC ; IF ; WB
Reactivity: Zebrafish
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Linda Ariza-McNaughton
Institute: Cancer Research UK, London Research Institute: Lincoln's Inn Fields
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-Zebrafish gut secretory cell epitopes [FIS 6G5/1]
- Research fields: Cell biology;Cell signaling and signal transduction;Developmental biology;Genetics;Stem cell biology;Tags and cell markers
- Clone: FIS 6G5/1
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Strain: Balb/c
- Reactivity: Zebrafish
- Host: Mouse
- Application: ELISA ; IHC ; IF ; WB
- Description: The transparency of the juvenile zebrafish and its genetic advantages make it an attractive model for the study of intestinal differentiation and renewal. This antibody labels the secretory cells of the zebrafish intestinal epithelium, both mucous and enteroendocrine, corresponding to the class of cells that are lost in MathI mouse mutants (Yang et al, (2001) Science 294: 2155-2158).
- Immunogen: Lysate of zebrafish intestine
- Isotype: IgG1
- Myeloma used: Sp2/0-Ag14
Target Details
- Target: Zebrafish gut secretory cell epitopes
- Target background: The transparency of the juvenile zebrafish and its genetic advantages make it an attractive model for the study of intestinal differentiation and renewal. This antibody labels the secretory cells of the zebrafish intestinal epithelium, both mucous and enteroendocrine, corresponding to the class of cells that are lost in MathI mouse mutants (Yang et al, (2001) Science 294: 2155-2158).
Applications
- Application: ELISA ; IHC ; IF ; WB
Handling
- Format: Liquid
- Concentration: 0.9 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
Related Tools
- Related tools: Anti-Zebrafish Basolateral Pole of Cells [FIS 2H9/1]
References
- Matthews et al. 2008. Dev Dyn. 237(1):124-31. PMID: 18095340.
- Transcription factor onecut3 regulates intrahepatic biliary development in zebrafish.
- Dong et al. 2007. Nat Genet. 39(3):397-402. PMID: 17259985.
- Fgf10 regulates hepatopancreatic ductal system patterning and differentiation.
- Bates et al. 2006. Dev Biol. 297(2):374-86. PMID: 16781702.
- Distinct signals from the microbiota promote different aspects of zebrafish gut differentiation.
- Crosnier et al. 2005. Development. 132(5):1093-104. PMID: 15689380.
- Delta-Notch signalling controls commitment to a secretory fate in the zebrafish intestine.
