#157724

Anti-uncarboxylated osteocalcin (ucOC) [Fab-2]

Cat. #157724

Anti-uncarboxylated osteocalcin (ucOC) [Fab-2]

Cat. #: 157724

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 10-12 weeks

Target: osteocalcin - partially carboxylated with Glu at position 17 and 21

Class: Recombinant

Application: IF ; Fn

Reactivity: Human

Host: Human

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Kaisa Ivaska-Papaioannou ; Urpo Lamminmäki

Institute: University of Turku

Tool Details
Target Details
Applications
Handling
Related Tools
References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: Anti-uncarboxylated osteocalcin (ucOC) [Fab-2]
  • Alternate name: Uncarboxylated osteocalcin, uc-Osteocalcin, uc-OC, bone gamma-carboxyglutamic acid-containing protein, BGLAP
  • Research fields: Disease (not cancer);Metabolism
  • Tool sub type: Primary antibody
  • Class: Recombinant
  • Purpose: Marker
  • Conjugation: Unconjugated
  • Reactivity: Human
  • Host: Human
  • Application: IF ; Fn
  • Description: Osteocalcin, also known as bone gamma-carboxyglutamic acid-containing protein (BGLAP), is a small (49-amino-acid) noncollagenous protein hormone found in bone and dentin. Osteocalcin is a bone-specific protein which contains three glutamic acid residues (Glu) that undergo post-translational gamma-carboxylation. Uncarboxylated osteocalcin (ucOC) may participate in the regulation of glucose metabolism, thus measurement of ucOC could be useful in evaluating interactions between bone and glucose ...
  • Immunogen: Human full-length ucOC peptide (149, Glu at positions 17, 21 and 24; C23C29 bridge)
  • Isotype: IgG1 kappa

Target Details

  • Target: osteocalcin - partially carboxylated with Glu at position 17 and 21
  • Tissue cell line specificity: Human
  • Target background: Osteocalcin, also known as bone gamma-carboxyglutamic acid-containing protein (BGLAP), is a small (49-amino-acid) noncollagenous protein hormone found in bone and dentin. Osteocalcin is a bone-specific protein which contains three glutamic acid residues (Glu) that undergo post-translational gamma-carboxylation. Uncarboxylated osteocalcin (ucOC) may participate in the regulation of glucose metabolism, thus measurement of ucOC could be useful in evaluating interactions between bone and glucose ...

Applications

  • Application: IF ; Fn

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Unit size: 100 ug
  • Storage conditions: -20° C
  • Shipping conditions: Shipping at 4° C

Related Tools

  • Related tools: Anti-uncarboxylated osteocalcin (ucOC) [Fab-16] recombinant antibody ; Anti-uncarboxylated osteocalcin (ucOC) [Fab-13] recombinant antibody ; Anti-uncarboxylated osteocalcin (ucOC) [Fab-19] recombinant antibody ; Anti-OC [Fab-12] recombinant antibody

References

  • Arponen et al. 2020. Calcif Tissue Int. 107(6):529-542. PMID: 32839842.