Anti- sodium/iodide symporter (NIS) [VJ1]

monoclonal antibody to human Sodium iodide symporter (NIS)

Contributors

Inventor Institute
Sabine Costagliola Universite Libre de Bruxelles
Cat. #: 161640
Tool sub type: Primary antibody
Cancer types: Thyroid cancer
Research Fields: Cancer
Application: FACS, IF, IHC, not WB after epitope denaturation
Target: Human Sodium iodide symporter (NIS), epitope between amino acid 272 and 515 located within the last three extracellular loops
Reactivity: Human
Clone: VJ1
Host: Mice
Class: Monoclonal
Primary citation: Costagliola et al. 2000. J Clin Endocrinol Metab. 85(7):2366-9. PMID: 10902780.
Product description: VJ1 is a monoclonal antibody to human NIS that recognizes an epitope located between amino acid 272 and 515 located within the last three extracellular loops
Isotype: IgG1,k
Immunogen: pCDNA3-hNIS (genetic immunization)
Target background: Sodium iodide symporter (NIS) is a gene responsible for the transport of iodide into the thyroid gland and is located in the basolateral membrane of thyroid follicular cells. NIS is also expressed in extrathyroidal tissues, including transformed cells, and its expression may be used as a biomarker for diagnostic, prognostic, and therapeutic purposes.
Shipping conditions: Dry ice

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