Anti-RACO1 [5H10]

RING-domain-containing protein (RACO-1) is a c-Jun co-activator that is regulated by the MEK signalling pathway. RACO-1 is a molecular link between growth factor signalling and AP-1. RACO-1 depletion reduces cellular proliferation and decreases expression of several growth-associated AP-1 target genes such as cdc2, cyclin D1 and hb-egf.

Contributors

Inventor Institute
Axel Behrens Cancer Research UK, London Research Institute: Lincoln's Inn Fields
Cat. #: 151685
Tool sub type: Primary antibody
Unit size: 100 ug
Research Fields: Cell signaling and signal transduction
Application: ELISA ; IP ; WB
Target: RACO1
Reactivity: Human ; Mouse ; Rat
Clone: 5H10
Host: Mouse
Class: Monoclonal
Alternate name: Ring Finger Protein 187; RING Domain AP1 Coactivator 1; Protein RNF187; RACO1
Product description: RING-domain-containing protein (RACO-1) is a c-Jun co-activator that is regulated by the MEK signalling pathway. RACO-1 is a molecular link between growth factor signalling and AP-1. RACO-1 depletion reduces cellular proliferation and decreases expression of several growth-associated AP-1 target genes such as cdc2, cyclin D1 and hb-egf.
Conjugation: Unconjugated
Isotype: IgG1
Immunogen: Single C-terminal immunogenic peptide
Myeloma used: Sp2/0-Ag14
Target background: RING-domain-containing protein (RACO-1) is a c-Jun co-activator that is regulated by the MEK signalling pathway. RACO-1 is a molecular link between growth factor signalling and AP-1. RACO-1 depletion reduces cellular proliferation and decreases expression of several growth-associated AP-1 target genes such as cdc2, cyclin D1 and hb-egf.
Format: Liquid
Concentration: 1 mg/ml
Storage buffer: PBS with 0.02% azide
Storage conditions: -15° C to -25° C
Shipping conditions: Dry ice
References:

Davies et al. 2010. Nat Cell Biol. 12(10):963-72. PMID: 20852630.

Identification of a co-activator that links growth factor signalling to c-Jun/AP-1 activation.

Related Tools for Antibodies

Cat. # Tool Name
151029 Anti-HSVICP8 [11E2] Key Info View Tool
151034 Anti-HSVUL42 [13D11] Key Info View Tool
151036 Anti-ICAM1 [15.2] Key Info View Tool
151039 Anti-Integrin aVb3 [23C6] Key Info View Tool
151028 Anti-Cytochrome P450 2C2, 2B1/2 [h7] Key Info View Tool

Tool enquiry

Please ensure you use your organisation email address rather than personal where possible, as this helps us locate your organisation in our system faster.

Please note we may take up to three days to respond to your enquiry.

CancerTools.org uses the contact information provided to respond to you about our research tools and service. For more information please review our privacy policy.