Profilin is a low-molecular weight, actin monomer-binding protein that regulates the organization of actin cytoskeleton in eukaryotes.
| Inventor | Institute |
|---|---|
| Richard Meager | University of Georgia |
| Cat. #: | 153912 |
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| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cell biology |
| Application: | IF ; WB |
| Target: | Profilin 1 |
| Reactivity: | Arabidopsis |
| Host: | Mouse |
| Class: | Monoclonal |
| Alternate name: | PRF1 |
|---|---|
| Product description: | Profilin is a low-molecular weight, actin monomer-binding protein that regulates the organization of actin cytoskeleton in eukaryotes. Profilin promotes actin assembly at the barbed end of filaments and causes depolymerization of filaments by binding and sequestering G-actin. Profilin also interacts with several other ligands, such as membrane polyphospho-inositides, short proline rich stretches in proteins, and the Arp 2/3 complex. |
| Conjugation: | Unconjugated |
| Isotype: | IgG2a |
| Immunogen: | Purified plant Profilin 1 |
| Target background: | Profilin is a low-molecular weight, actin monomer-binding protein that regulates the organization of actin cytoskeleton in eukaryotes. Profilin promotes actin assembly at the barbed end of filaments and causes depolymerization of filaments by binding and sequestering G-actin. Profilin also interacts with several other ligands, such as membrane polyphospho-inositides, short proline rich stretches in proteins, and the Arp 2/3 complex. |
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| Format: | Liquid |
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| Shipping conditions: | Dry ice |
| References: |
Kandasamy et al. 2002. Cell Motil Cytoskeleton. 52(1):22-32. PMID: 11977080. Plant profilin isovariants are distinctly regulated in vegetative and reproductive tissues. |
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