Cat. #162375

Anti-PAX9 monoclonal antibody [PAX9 7C2]

Name: Anti-PAX9 monoclonal antibody [PAX9 7C2]
SKU: 162375
Availability: InStock

Cat. #: 162375

Sub-type: Primary antibody

Target: Human/murine PAX9

Class: Monoclonal

Application: WB

Reactivity: Human, mouse

Host: Rat

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

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Contributor

Institute: Helmholtz Munich Core Facility Monoclonal Antibodies

Primary Citation: Gerber et al. 2002. J. Pathol. 197: 293-297. PMID: 12115874

Tool Details

Target Details

Applications

References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

Name: Anti-PAX9 monoclonal antibody [PAX9 7C2]
Alternate name: Anti human/murine PAX9 monoclonal antibody (clone PAX9 7C2)
Cancer type: Lung cancer, Head and neck cancer
Research fields: Cell biology;Cell signaling and signal transduction;Developmental biology
Clone: PAX9 7C2
Tool type ecom: Antibody
Tool sub type: Primary antibody
Class: Monoclonal
Conjugation: Unconjugated
Reactivity: Human, mouse
Host: Rat
Disease: Cancer
Application: WB
Isotype: IgG1, k

Target Details

Target: Human/murine PAX9
Target alternate names: Paired Box Protein Pax-9, STHAG3
Target background: PAX9 has prognostic significance in esophageal squamous cell carcinoma (ESCC) and predicts radiation sensitivity. Progressive loss of PAX9 expression correlates with increasing malignancy of dysplastic and cancerous epithelium of the human oesophagus. PAX9 expression has been shown to mediate oncogene-induced cell survival in oral squamous cell carcinoma (Lee et al., 2008). On the other hand progressive loss of PAX9 expression correlates with increasing malignancy in esophageal cancers (Gerber et al., 2002)

Applications

Application: WB

References

Gerber et al. 2002. J. Pathol. 197: 293-297. PMID: 12115874
Jonker et al. 2004. Mech. Dev. 121: 1313-1322. PMID: 15454262