Monoclonal antibody which specifically binds vascular endothelium tissue.
| Inventor | Institute |
|---|---|
| Nancy Hogg | Cancer Research UK, London Research Institute: Lincoln's Inn Fields |
| Cat. #: | 151025 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cancer;Cell biology;Tissue-specific biology |
| Application: | IHC |
| Target: | Vascular endothelium marker |
| Reactivity: | Human |
| Clone: | 10 |
| Host: | Mouse |
| Class: | Monoclonal |
| Product description: | Monoclonal antibody which specifically binds vascular endothelium tissue. |
|---|---|
| Conjugation: | Unconjugated |
| Isotype: | IgM |
| Immunogen: | Fibronectin-purified human monocytes. |
| Myeloma used: | Sp2/0-Ag14 |
| Target background: | The vascular endothelium comprises the thin inner layer of cells lining arteries and veins, with an essential role in the regulation of blood vessel tone and cellular activity. This antibody may be used to study the synovial membrane in rheumatoid, osteoarthritic and traumatised joints as well as normal vasculature. Anti-vascular endothelium (10) reactivity is stronger on capillary endothelium and weaker on larger arteries and veins. |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | Store at -20° C frozen. Avoid repeated freeze / thaw cycles |
| Shipping conditions: | Dry ice |
| References: |
Palmer et al. 1985. Clin Exp Immunol. 59(3):529-38. PMID: 3886218. Features of synovial membrane identified with monoclonal antibodies. |
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