#151016

Anti-CyclinA [E72.1]

Cat. #151016

Anti-CyclinA [E72.1]

Cat. #: 151016

Sub-type: Primary antibody

Unit size: 100 ug

Target: Cyclin A

Class: Monoclonal

Application: IHC ; IF ; IP ; WB

Reactivity: Bovine

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Julian Gannon

Institute: Cancer Research UK, London Research Institute: Clare Hall Laboratories

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: Anti-CyclinA [E72.1]
  • Alternate name: CCNA1; Cyclin A1; Testicular Tissue Protein Li 34; CT146
  • Research fields: Cancer;Cell biology;Genetics
  • Clone: E72.1
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Reactivity: Bovine
  • Host: Mouse
  • Application: IHC ; IF ; IP ; WB
  • Description: Cyclins bind to and regulate the activity of the Cyclin Dependent Protein Kinases (CDKs). Cyclin A is involved in the regulation of the cell cycle and is essential for progression through S phase. Cyclin A protein is absent in cells prior to S-phase, during which its levels increase and peak. Cyclin A is a marker for actively proliferating cells and for cells in S phase.
  • Immunogen: Bovine Cyclin A
  • Isotype: IgG1
  • Myeloma used: Sp2/0-Ag14

Target Details

  • Target: Cyclin A
  • Target background: Cyclins bind to and regulate the activity of the Cyclin Dependent Protein Kinases (CDKs). Cyclin A is involved in the regulation of the cell cycle and is essential for progression through S phase. Cyclin A protein is absent in cells prior to S-phase, during which its levels increase and peak. Cyclin A is a marker for actively proliferating cells and for cells in S phase.

Applications

  • Application: IHC ; IF ; IP ; WB

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C

References

  • Garner et al. 2002. Oncogene. 21(53):8089-104. PMID: 12444545.
  • Delta MEKK3:ER* activation induces a p38 alpha/beta 2-dependent cell cycle arrest at the G2 checkpoint.
  • Bashir et al. 2000. Proc Natl Acad Sci U S A. 97(10):5522-7. PMID: 10792046.
  • Cyclin A activates the DNA polymerase delta -dependent elongation machinery in vitro: A parvovirus DNA replication model.