Cat. #151016
Anti-CyclinA [E72.1]
Cat. #: 151016
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 10-12 weeks
Target: Cyclin A
Class: Monoclonal
Application: IHC ; IF ; IP ; WB
Reactivity: Bovine
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Julian Gannon
Institute: Cancer Research UK, London Research Institute: Clare Hall Laboratories
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-CyclinA [E72.1]
- Alternate name: CCNA1; Cyclin A1; Testicular Tissue Protein Li 34; CT146
- Research fields: Cancer;Cell biology;Genetics
- Clone: E72.1
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Reactivity: Bovine
- Host: Mouse
- Application: IHC ; IF ; IP ; WB
- Description: Cyclins bind to and regulate the activity of the Cyclin Dependent Protein Kinases (CDKs). Cyclin A is involved in the regulation of the cell cycle and is essential for progression through S phase. Cyclin A protein is absent in cells prior to S-phase, during which its levels increase and peak. Cyclin A is a marker for actively proliferating cells and for cells in S phase.
- Immunogen: Bovine Cyclin A
- Isotype: IgG1
- Myeloma used: Sp2/0-Ag14
Target Details
- Target: Cyclin A
- Target background: Cyclins bind to and regulate the activity of the Cyclin Dependent Protein Kinases (CDKs). Cyclin A is involved in the regulation of the cell cycle and is essential for progression through S phase. Cyclin A protein is absent in cells prior to S-phase, during which its levels increase and peak. Cyclin A is a marker for actively proliferating cells and for cells in S phase.
Applications
- Application: IHC ; IF ; IP ; WB
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: '-15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Garner et al. 2002. Oncogene. 21(53):8089-104. PMID: 12444545.
- Delta MEKK3:ER* activation induces a p38 alpha/beta 2-dependent cell cycle arrest at the G2 checkpoint.
- Bashir et al. 2000. Proc Natl Acad Sci U S A. 97(10):5522-7. PMID: 10792046.
- Cyclin A activates the DNA polymerase delta -dependent elongation machinery in vitro: A parvovirus DNA replication model.
