#153987

Anti-O-GlcNAc (CTD110.6)

Cat. #153987

Anti-O-GlcNAc (CTD110.6)

Cat. #: 153987

Sub-type: Primary antibody

Unit size: 100 ug

Target: ?-O-linked N-acetylglucosamine (O-GlcNAc) in ?-O-glycosidic linkage to both serine and threonine and does not cross react with a-linked Ser/Thr-O-GlcNAc, a-linked Ser-O-linked N-acetylgalactosamine or N-linked oligosaccharides on ovalbumin and immunoglobulin G.

Class: Monoclonal

Application: ELISA ; IHC ; IP ; WB

Reactivity: Human ; Mouse ; Primate ; Rat ; All

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Gerald Hart

Institute: Johns Hopkins University

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-O-GlcNAc (CTD110.6)
  • Research fields: Biochemistry;Cell signaling and signal transduction
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Purpose: Marker
  • Conjugation: Unconjugated
  • Reactivity: Human ; Mouse ; Primate ; Rat ; All
  • Host: Mouse
  • Application: ELISA ; IHC ; IP ; WB
  • Description: The ?-O-linked N-acetylglucosamine (O-GlcNAc) antibody recognizes glycosylation, a post-translational modification, which occurs on serine and threonine residues of proteins in the nuclear and cytoplasmic compartments. This type of glycosylation results in a single moiety and not a complex branched structure. The O-GlcNAc antibody does not cross react with ?-linked Ser/Thr-O-GlcNAc, ?-linked Ser-O-linked N-acetylgalactosamine or N-linked oligosaccharides on ovalbumin and immunoglobulin G.
  • Immunogen: Synthetic glycopeptide (YSPTS(O-GlcNAc)PSK)
  • Isotype: IgM

Target Details

  • Target: ?-O-linked N-acetylglucosamine (O-GlcNAc) in ?-O-glycosidic linkage to both serine and threonine and does not cross react with a-linked Ser/Thr-O-GlcNAc, a-linked Ser-O-linked N-acetylgalactosamine or N-linked oligosaccharides on ovalbumin and immunoglobulin G.
  • Tissue cell line specificity: Mouse
  • Target background: The ?-O-linked N-acetylglucosamine (O-GlcNAc) antibody recognizes glycosylation, a post-translational modification, which occurs on serine and threonine residues of proteins in the nuclear and cytoplasmic compartments. This type of glycosylation results in a single moiety and not a complex branched structure. The O-GlcNAc antibody does not cross react with a-linked Ser/Thr-O-GlcNAc, a-linked Ser-O-linked N-acetylgalactosamine or N-linked oligosaccharides on ovalbumin and immunoglobulin G.

Applications

  • Application: ELISA ; IHC ; IP ; WB

Handling

  • Format: Liquid
  • Unit size: 100 ug
  • Storage conditions: -20° C
  • Shipping conditions: Shipping at 4° C

References

  • Comer et al. 2001. Anal Biochem. 293(2):169-77. PMID: 11399029.
  • Characterization of a mouse monoclonal antibody specific for O-linked N-acetylglucosamine.