#151708

Anti-MTBP [2C1E11]

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Cat. #151708

Anti-MTBP [2C1E11]

Cat. #: 151708

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 1-2 weeks

Target: MTBP

Class: Monoclonal

Application: WB

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Mark Boyd

Institute: University of Liverpool

Tool Details
Target Details
Applications
Handling
Related Tools
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-MTBP [2C1E11]
  • Alternate name: MDM2 Binding Protein, MDM2 (Mouse Double Minute 2)-Binding Protein, Mdm2, Transformed 3T3 Cell Double Minute 2, P53 Binding Protein (Mouse) Binding Protein, Mdm2, Transformed 3T3 Cell Double Minute 2, P53 Binding Protein Binding Protein, MDM2BP, HMTBP
  • Research fields: Cancer;Cell biology;Genetics
  • Clone: 2C1E11
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Application: WB
  • Description: MTBP is an MDM2 binding protein that alters p53/MDM2 homeostasis and may contribute to metastatic suppression. Recent studies have demonstrated that loss of MTBP expression in samples that are p53 positive and have low MDM2 is significantly associated with reduced patient survival in Squamous cell carcinoma of the head and neck (SCCHN).
  • Immunogen: Recombinant full-length human MTBP
  • Isotype: IgG1 kappa

Target Details

  • Target: MTBP
  • Target background: MTBP is an MDM2 binding protein that alters p53/MDM2 homeostasis and may contribute to metastatic suppression. Recent studies have demonstrated that loss of MTBP expression in samples that are p53 positive and have low MDM2 is significantly associated with reduced patient survival in Squamous cell carcinoma of the head and neck (SCCHN).

Applications

  • Application: WB

Handling

  • Format: Liquid
  • Concentration: 1.1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C

Related Tools

  • Related tools: Anti-MTBP [2C1G6]

References

  • Vlatkovic et al. 2011. Cancer. 117(13):2939-50. PMID: 21692053.
  • Loss of MTBP expression is associated with reduced survival in a biomarker-defined subset of patients with squamous cell carcinoma of the head and neck.