![Western blot analysis of lysates prepared from U20S cells transfected with myc-MOAP-1 (+) or vector control (-). Detection was performed using an anti-Myc antibody or anti-MOAP-1 [4A12]](https://cancertools.org/wp-content/uploads/cfd9d905-74bc-4068-af2c-65c4def0b061.png)
![Anti-MOAP-1 [4A12] - Image 2](https://cancertools.org/wp-content/uploads/684ebd6d-4d17-4227-ab0c-0f8cdb99c52e.png)
Cat. #152644
Anti-MOAP-1 [4A12]
Cat. #: 152644
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 10-12 weeks
Target: Modulator of apoptosis-1
Class: Monoclonal
Application: IF ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Institute: A*STAR Accelerate Technologies Pte Ltd
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-MOAP-1 [4A12]
- Research fields: Apoptosis and autophagy;Cancer
- Clone: 4A12
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Reactivity: Human
- Host: Mouse
- Application: IF ; WB
- Description: MOAP-1, also known as MAP-1 (Modulator of apoptosis-1) was initially identified as a Bax-associating protein from a yeast two-hybrid screen using Bax as bait. MOAP-1 is enriched in mitochondria and appears to be an effector for mediating Bax function in mitochondria. Moreover, in supporting the idea that MOAP-1 may be involved in a tumor suppressor axis, MOAP-1 is found to associate with the tumor suppressor RASSF1A to mediate Bax-dependent apoptosis in response to death receptor activation in tumor cells.
- Immunogen: GST-MOAP-1 (N-terminal) fusion protein
- Isotype: IgG1
- Myeloma used: Sp2/0-Ag14
Target Details
- Target: Modulator of apoptosis-1
- Target background: MOAP-1, also known as MAP-1 (Modulator of apoptosis-1) was initially identified as a Bax-associating protein from a yeast two-hybrid screen using Bax as bait. MOAP-1 is enriched in mitochondria and appears to be an effector for mediating Bax function in mitochondria. Moreover, in supporting the idea that MOAP-1 may be involved in a tumor suppressor axis, MOAP-1 is found to associate with the tumor suppressor RASSF1A to mediate Bax-dependent apoptosis in response to death receptor activation in tumor cells.
Applications
- Application: IF ; WB
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
