Cat. #154782
Anti-Melanoma Associated Antigen 100 (Gp100) [Beteb]
Cat. #: 154782
Sub-type: Primary antibody
Unit size: 100 ug
Target: Melanoma Associated Antigen 100
Class: Monoclonal
Application: IHC
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Institute: Netherlands Cancer Institute
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-Melanoma Associated Antigen 100 (Gp100) [Beteb]
- Research fields: Cancer;Cell biology
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 70 kDa
- Strain: Balb/c
- Reactivity: Human
- Host: Mouse
- Application: IHC
- Description: Gp100 plays a central role in the biogenesis of melanosomes. Involved in the maturation of melanosomes from stage I to II. The transition from stage I melanosomes to stage II melanosomes involves an elongation of the vesicle, and the appearance within of distinct fibrillar structures. Release of the soluble form, ME20-S, could protect tumour cells from antibody mediated immunity.
- Immunogen: Purified membranes of a human melanoma lymph node metastasis
- Isotype: IgG2b
- Myeloma used: Sp2/0-Ag14
Target Details
- Target: Melanoma Associated Antigen 100
- Molecular weight: 70 kDa
- Target background: Gp100 plays a central role in the biogenesis of melanosomes. Involved in the maturation of melanosomes from stage I to II. The transition from stage I melanosomes to stage II melanosomes involves an elongation of the vesicle, and the appearance within of distinct fibrillar structures. Release of the soluble form, ME20-S, could protect tumour cells from antibody mediated immunity.
Applications
- Application: IHC
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Vennegoor et al. 1988. Am J Pathol. 130(1):179-92. PMID: 3276209.
