Human lymphocyte-specific protein 1 is an F-actin binding phosphoprotein, which has an acidic N-terminal half and a basic C-terminal half. In the basic C-terminal half, there are amino acid sequences highly homologous to the actin-binding domains of two known F-actin binding proteins: caldesmon and the villin headpieces (CI, CII, VI, VII).
| Inventor | Institute |
|---|---|
| Karen Pulford | University of Oxford |
| Cat. #: | 151397 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cell signaling and signal transduction;Immunology |
| Application: | IHC ; IP ; WB |
| Target: | Lymphocyte Specific Protein-1 (LSP1) |
| Reactivity: | Human |
| Clone: | TPD153 |
| Host: | Mouse |
| Class: | Monoclonal |
| Product description: | Human lymphocyte-specific protein 1 is an F-actin binding phosphoprotein, which has an acidic N-terminal half and a basic C-terminal half. In the basic C-terminal half, there are amino acid sequences highly homologous to the actin-binding domains of two known F-actin binding proteins: caldesmon and the villin headpieces (CI, CII, VI, VII). |
|---|---|
| Conjugation: | Unconjugated |
| Isotype: | IgG1 kappa |
| Immunogen: | Tonsil cells |
| Myeloma used: | P3/NS1/1-Ag4.1 |
| Target background: | Human lymphocyte-specific protein 1 is an F-actin binding phosphoprotein, which has an acidic N-terminal half and a basic C-terminal half. In the basic C-terminal half, there are amino acid sequences highly homologous to the actin-binding domains of two known F-actin binding proteins: caldesmon and the villin headpieces (CI, CII, VI, VII). |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Marafioti et al. 2004. Haematologica. 89(8):957-64. PMID: 15339679. Leukocyte-specific phosphoprotein-1 and PU.1: two useful markers for distinguishing T-cell-rich B-cell lymphoma from lymphocyte-predominant Hodgkin's disease. Marafioti et al. 2003. Br J Haematol. 120(4):671-8. PMID: 12588355. Leucocyte-specific protein (LSP1) in malignant lymphoma and Hodgkin's disease. Pulford et al. 1999. Immunology. 96(2):262-71. PMID: 10233704. Lymphocyte-specific protein 1: a specific marker of human leucocytes. |
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