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#151343

Anti-Leu1 [CD5/54/F6]

Cat. #151343

Anti-Leu1 [CD5/54/F6]

Cat. #: 151343

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 3-4 weeks

Target: Leu1 (CD5)

Class: Monoclonal

Application: IHC ; WB

Reactivity: Bovine ; Chicken ; Horse ; Guinea Pig ; Opossum ; Pig ; Primate ; Rat ; Rabbit

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Jacqueline Cordell

Institute: University of Oxford

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: Anti-Leu1 [CD5/54/F6]
  • Alternate name: CD5 Molecule 2; Lymphocyte Antigen T1/Leu-1; LEU1; CD5 Antigen; T1
  • Cancer: Blood cancer
  • Cancers detailed: Leukemia;Lymphoma
  • Research fields: Immunology;Stem cell biology
  • Clone: CD5/54/F6
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Purpose: Marker
  • Conjugation: Unconjugated
  • Reactivity: Bovine ; Chicken ; Horse ; Guinea Pig ; Opossum ; Pig ; Primate ; Rat ; Rabbit
  • Host: Mouse
  • Application: IHC ; WB
  • Description: CD5 is a surface glycoprotein present on peripheral T cells (>95%) and B-cell chronic lymphocytic leukaemia cells that binds CD72. CD5 has utility for the monitoring of T-cell numbers in peripheral blood and the identification of leukaemias of T cell origin. Absence of the CD5 marker on childhood ALL cells is associated with a more favourable prognosis. Detects CD5 on mammalian tissue
  • Immunogen: Peptide from the intracellular region of CD5 (SSMQPDNSSDSDYDLHGAQRL)
  • Isotype: IgG1
  • Myeloma used: P3/NS1/1-Ag4.1

Target Details

  • Target: Leu1 (CD5)
  • Tissue cell line specificity: Mouse
  • Target background: CD5 is a surface glycoprotein present on peripheral T cells (>95%) and B-cell chronic lymphocytic leukaemia cells that binds CD72. CD5 has utility for the monitoring of T-cell numbers in peripheral blood and the identification of leukaemias of T cell origin. Absence of the CD5 marker on childhood ALL cells is associated with a more favourable prognosis. Detects CD5 on mammalian tissue

Applications

  • Application: IHC ; WB

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Dry ice

References

  • Jones et al. 1993. J Immunol. 150(12):5429-35. PMID: 8515069.
  • Detection of T and B cells in many animal species using cross-reactive anti-peptide antibodies.

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