Cat. #151124
Anti-Keratin7 [LP1K]
Cat. #: 151124
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-4 weeks
Target: Keratin 7
Class: Monoclonal
Application: IHC ; IF ; WB
Reactivity: Mammalian ; Xenopus laevis
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Birgit Lane
Institute: Queen Mary University of London
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-Keratin7 [LP1K]
- Research fields: Cell signaling and signal transduction
- Clone: LP1K
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 54 kDa
- Strain: Balb/c
- Reactivity: Mammalian ; Xenopus laevis
- Host: Mouse
- Application: IHC ; IF ; WB
- Description: Monoclonal antibody which binds keratin 7.
- Immunogen: Sonicated cytoskeleton fractions (insoluble in 1% Nonidet-P40) from SV40 transformed neonatal keratinocytes.
- Immunogen uniprot id: P08729
- Isotype: IgG1
- Myeloma used: Sp2/0-Ag14
Target Details
- Target: Keratin 7
- Molecular weight: 54 kDa
- Target background: Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Keratins 7 and 8 are two closely related type II keratins characteristic of simple epithelia. Keratin 7 is less widespread than keratin 8 and is expressed in sebaceous and sweat glands, blood vessels and some cells of the inner hair root sheath. Keratin 7 is often co-expressed with keratin 19. LP1K has some weak reactivity with keratin 8 and other type II keratins.
Applications
- Application: IHC ; IF ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: Store at -20° C frozen. Avoid repeated freeze / thaw cycles
- Shipping conditions: Dry ice
References
- Lane EB et al. 1985. Ann. NY Acad. Sci. 455:241-58.PMID: 2417515
- Reyes et al. 2018. J Oral Microbiol. 10(1):1374153. PMID: 29291034.
- Yougbar et al. 2017. Nat Commun. 8(1):224. PMID: 28794456.
- Devos et al. 2017. J Invest Dermatol. 137(2):494-505. PMID: 27725202.
- Zhang et al. 2015. Reproduction. 150(2):139-49. PMID: 26021998.
- Zhang et al. 2013. Cell Death Dis. 4:e502. PMID: 23429288.
- CUL1 promotes trophoblast cell invasion at the maternal-fetal interface.
- Zhang et al. 2012. PLoS One. 7(6):e38487. PMID: 22679510.
- Expression of CD82 in human trophoblast and its role in trophoblast invasion.
- Markey et al. 1992. Br J Dermatol. 126(2):154-60. PMID: 1371396.
- Keratin expression in basal cell carcinomas.
