Lewis X (CD15) is a branched pentasaccharide found on neutrophils, eosinophils and monocytes. Lewis X is distributed abnormally in myeloid leukeamias and is commonly used in the diagnosis of Hodgkin’s disease. It can also be used for analysis of myeloid leukaemias and studies of myeloid differentiation.
| Inventor | Institute |
|---|---|
| Nancy Hogg | Cancer Research UK, London Research Institute: Lincoln's Inn Fields |
| Cat. #: | 151041 |
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| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cancer;Immunology |
| Application: | IHC ; IP ; FACS ; IHC ; IP |
| Target: | Lewis X (CD15) |
| Reactivity: | Human |
| Clone: | 28 |
| Host: | Mouse |
| Class: | Monoclonal |
| Primary citation: | Hogg et al. 1984. Immunology. 53(4):753-67. PMID: 6389324. |
| Alternate name: | Fucosyltransferase 4; Galactoside 3-L-Fucosyltransferase; ELAM-1 Ligand Fucosyltransferase; FUC-TIV; FCT3A; ELFT; Stage-Specific Embryonic Antigen; Alpha (1,3) Fucosyltransferase; EC 2.4.1.65; Lewis X; SSEA-1; FUTIV; CD15; LeX |
|---|---|
| Product description: | Lewis X (CD15) is a branched pentasaccharide found on neutrophils, eosinophils and monocytes. Lewis X is distributed abnormally in myeloid leukeamias and is commonly used in the diagnosis of HodgkinÄËĂÂĂÂs disease. It can also be used for analysis of myeloid leukaemias and studies of myeloid differentiation. |
| Conjugation: | Unconjugated |
| Isotype: | IgM |
| Molecular weight: | 83 kDa |
| Immunogen: | Monocytes, separated from other peripheral blood leucocytes (PBL) on fibronectin plates. |
| Myeloma used: | Sp2/0-Ag14 |
| Target background: | Lewis X (CD15) is a branched pentasaccharide found on neutrophils, eosinophils and monocytes. Lewis X is distributed abnormally in myeloid leukeamias and is commonly used in the diagnosis of Hodgkin's disease. It can also be used for analysis of myeloid leukaemias and studies of myeloid differentiation. |
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| Format: | Liquid |
|---|---|
| Concentration: | 0.71 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -80° C |
| Shipping conditions: | Dry ice |
| References: |
Hogg et al. 1984. Immunology. 53(4):753-67. PMID: 6389324. Monoclonal antibodies specific for human monocytes, granulocytes and endothelium. Linch et al. 1984. Blood. 63(3):566-73. PMID: 6365201. Monoclonal antibodies differentiating between monocytic and nonmonocytic variants of AML. |
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