Cat. #151222
Anti-Integrin b1 [4B7]
Cat. #: 151222
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-4 weeks
Target: Integrin ?1 (CD29)
Class: Monoclonal
Application: FACS ; IHC ; IF ; IP ; Fn
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Institute: Queen Mary University of London
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-Integrin b1 [4B7]
- Research fields: Cell biology;Developmental biology;Drug development;Stem cell biology
- Clone: 4B7
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Strain: Balb/c
- Reactivity: Human
- Host: Mouse
- Application: FACS ; IHC ; IF ; IP ; Fn
- Description: Integrins are heterodimeric cell surface receptors composed of alpha and beta subunits, which mediate cell-cell and cell-extracellular matrix attachments. Aberrant integrin expression has been found in many epithelial tumours. Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melanoma cells. Loss of integrin beta 1 is associated with the development of some epithelial tumours.
- Immunogen: Ocular melanoma cell line V+B2
- Isotype: IgG1
Target Details
- Target: Integrin ?1 (CD29)
- Target background: Integrins are heterodimeric cell surface receptors composed of alpha and beta subunits, which mediate cell-cell and cell-extracellular matrix attachments. Aberrant integrin expression has been found in many epithelial tumours. Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melanoma cells. Loss of integrin beta 1 is associated with the development of some epithelial tumours.
Applications
- Application: FACS ; IHC ; IF ; IP ; Fn
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Marshall et al. 1998. Br J Cancer. 77(4):522-9. PMID: 9484806.
- Comparative analysis of integrins in vitro and in vivo in uveal and cutaneous melanomas.
