Cat. #151109
Anti-Integrin a3 [IA3]
Cat. #: 151109
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-4 weeks
Target: Integrin a3 (CD49c)
Class: Monoclonal
Application: FACS ; IHC ; IF ; Fn
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Joyce Taylor-Papadimitriou
Institute: Cancer Research UK, London Research Institute: Lincoln's Inn Fields
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-Integrin a3 [IA3]
- Research fields: Cell biology;Cancer
- Clone: IA3
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 180-220 kDa
- Strain: Balb/c
- Reactivity: Human
- Host: Mouse
- Application: FACS ; IHC ; IF ; Fn
- Description: Monoclonal antibody with use studying inhibition of cellular adhesion.
- Immunogen: Transfected human breast epithelial cell line MTSV1-7, hygromycin resistant.
- Immunogen uniprot id: P26006
- Isotype: IgG1
- Myeloma used: P3X63Ag8.653
Target Details
- Target: Integrin a3 (CD49c)
- Molecular weight: 180-220 kDa
- Target background: Monoclonal antibody with use studying inhibition of cellular adhesion.
Applications
- Application: FACS ; IHC ; IF ; Fn
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: Store at -20° C frozen. Avoid repeated freeze / thaw cycles
- Shipping conditions: Shipping at 4° C
References
- Tremblay et al. 2017. Sci Rep. 7:46574. PMID: 28422167.
- Tremblay et al. 2017. Sci Rep. 7:46574. PMID: 28422167.
- Seltmann et al. 2015. J Invest Dermatol. 135(6):1609-1620. PMID: 25668239.
- Seltmann et al. 2015. J Invest Dermatol. 135(6):1609-20. PMID: 25668239.
- Keratins Stabilize Hemidesmosomes through Regulation of ?4-Integrin Turnover.
- Stawikowski et al. 2014. J Biol Chem. 289(31):21591-604. PMID: 24958723.
- Glycosylation modulates melanoma cell a2?1 and a3?1 integrin interactions with type IV collagen.
- Pytlk et al. 2009. Biomaterials. 30(20):3415-27. PMID: 19362364.
- The cultivation of human multipotent mesenchymal stromal cells in clinical grade medium for bone tissue engineering.
- Turner et al. 2006. Circulation. 114(8):820-9. PMID: 16908762.
- Alpha2(VIII) collagen substrata enhance endothelial cell retention under acute shear stress flow via an alpha2beta1 integrin-dependent mechanism: an in vitro and in vivo study.
- Berdichevsky et al. 1994. J Cell Sci. 107 ( Pt 12):3557-68. PMID: 7535787.
- Branching morphogenesis of human mammary epithelial cells in collagen gels.
