#153647

Anti-Inhibin a [PO12/8]

Please Enter Your Email ID
Email ID

Cat. #153647

Anti-Inhibin a [PO12/8]

Cat. #: 153647

Sub-type: Primary antibody

Unit size: 100 ug

Target: Inhibin a

Class: Monoclonal

Application: ELISA ; IHC

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Institute: BioServ UK Ltd

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-Inhibin a [PO12/8]
  • Alternate name: Inhibin alpha chain, INHA
  • Research fields: Cancer;Cell signaling and signal transduction
  • Clone: PO12/8
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Molecular weight: 40 kDa
  • Strain: Balb/c
  • Reactivity: Human
  • Host: Mouse
  • Application: ELISA ; IHC
  • Description: Higher levels of inhibin Î? have been associated with a higher risk of cancer progression and recurrence. Clone PO 12/8 is useful in detecting inhibin Î? levels, especially in prostate cancer cells.
  • Immunogen: Synthetic peptide corresponding to epitope region aa73-96 of the aC region of a subunit of inhibin A
  • Isotype: IgG2a
  • Myeloma used: Sp2/0-Ag14
  • Recommended controls: Prostate tissue

Target Details

  • Target: Inhibin a
  • Molecular weight: 40 kDa
  • Tissue cell line specificity: Prostate tissue
  • Target background: Higher levels of inhibin a have been associated with a higher risk of cancer progression and recurrence. Clone PO 12/8 is useful in detecting inhibin a levels, especially in prostate cancer cells.

Applications

  • Application: ELISA ; IHC

Handling

  • Format: Liquid
  • Unit size: 100 ug
  • Shipping conditions: Shipping at 4° C

References

  • Balanathan et al. 2009. Br J Cancer. 100(11):1784-93. PMID: 19436293.
  • Elevated level of inhibin-alpha subunit is pro-tumourigenic and pro-metastatic and associated with extracapsular spread in advanced prostate cancer.
  • Risbridger et al. 2004. Mol Cell Endocrinol. 225(1-2):73-6. PMID: 15451570.
  • Re-evaluation of inhibin alpha subunit as a tumour suppressor in prostate cancer.
  • Robertson et al. 2001. Mol Cell Endocrinol. 180(1-2):79-86. PMID: 11451575.
  • Development of an inhibin alpha subunit ELISA with broad specificity.