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Cat. #153647
Anti-Inhibin a [PO12/8]
Cat. #: 153647
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 10-12 weeks
Target: Inhibin a
Class: Monoclonal
Application: ELISA ; IHC
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Institute: BioServ UK Ltd
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-Inhibin a [PO12/8]
- Alternate name: Inhibin alpha chain, INHA
- Research fields: Cancer;Cell signaling and signal transduction
- Clone: PO12/8
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 40 kDa
- Strain: Balb/c
- Reactivity: Human
- Host: Mouse
- Application: ELISA ; IHC
- Description: Higher levels of inhibin ÄÂ? have been associated with a higher risk of cancer progression and recurrence. Clone PO 12/8 is useful in detecting inhibin ÄÂ? levels, especially in prostate cancer cells.
- Immunogen: Synthetic peptide corresponding to epitope region aa73-96 of the aC region of a subunit of inhibin A
- Isotype: IgG2a
- Myeloma used: Sp2/0-Ag14
- Recommended controls: Prostate tissue
Target Details
- Target: Inhibin a
- Molecular weight: 40 kDa
- Tissue cell line specificity: Prostate tissue
- Target background: Higher levels of inhibin a have been associated with a higher risk of cancer progression and recurrence. Clone PO 12/8 is useful in detecting inhibin a levels, especially in prostate cancer cells.
Applications
- Application: ELISA ; IHC
Handling
- Format: Liquid
- Unit size: 100 ug
- Shipping conditions: Dry ice
References
- Balanathan et al. 2009. Br J Cancer. 100(11):1784-93. PMID: 19436293.
- Elevated level of inhibin-alpha subunit is pro-tumourigenic and pro-metastatic and associated with extracapsular spread in advanced prostate cancer.
- Risbridger et al. 2004. Mol Cell Endocrinol. 225(1-2):73-6. PMID: 15451570.
- Re-evaluation of inhibin alpha subunit as a tumour suppressor in prostate cancer.
- Robertson et al. 2001. Mol Cell Endocrinol. 180(1-2):79-86. PMID: 11451575.
- Development of an inhibin alpha subunit ELISA with broad specificity.
