Cat. #151110
Anti-ICAM3 [ICAM 3.1]
Cat. #: 151110
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-4 weeks
Target: ICAM3 (CD50)
Class: Monoclonal
Application: ELISA ; FACS ; IHC ; IF ; IP ; RIA ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Joyce Taylor-Papadimitriou
Institute: University of Oxford
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-ICAM3 [ICAM 3.1]
- Alternate name: Intercellular Adhesion Molecule 3; ICAM-3; ICAM-R; CDW5; CD5
- Research fields: Cell biology;Cell signaling and signal transduction;Immunology
- Clone: ICAM 3.1
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 130 kDa
- Strain: Balb/c
- Reactivity: Human
- Host: Mouse
- Application: ELISA ; FACS ; IHC ; IF ; IP ; RIA ; WB
- Description: ICAMs are members of the immunoglobulin superfamily that is characterised by the presence of immunoglobulin-like domains. ICAM-3 is the major ligand for LFA-1 (CD11a/CD18) in the resting state. ICAM-3 may play a key role in initiating immune responses. ICAM 3.1 and ICAM 3.2 can be used to examine LFA-1/ICAM-3 adhesion.
- Immunogen: ICAM-3Fc chimeric fusion protein.
- Immunogen uniprot id: P26006
- Isotype: IgG1 kappa
- Myeloma used: Sp2/0-Ag14
Target Details
- Target: ICAM3 (CD50)
- Molecular weight: 130 kDa
- Target background: ICAMs are members of the immunoglobulin superfamily that is characterised by the presence of immunoglobulin-like domains. ICAM-3 is the major ligand for LFA-1 (CD11a/CD18) in the resting state. ICAM-3 may play a key role in initiating immune responses. ICAM 3.1 and ICAM 3.2 can be used to examine LFA-1/ICAM-3 adhesion.
Applications
- Application: ELISA ; FACS ; IHC ; IF ; IP ; RIA ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Dry ice
References
- DC-SIGN binds ICAM-3 isolated from peripheral human leukocytes through Lewis x residues.
- Increase in lymphoid follicles and leukocyte adhesion molecules emphasizes a role for the gut in spondyloarthropathy pathogenesis.
- Analysis of the binding site on intercellular adhesion molecule 3 for the leukocyte integrin lymphocyte function-associated antigen 1.
