Anti-HuR [4C8] (ChIP Grade)

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

• Name: Anti-HuR [4C8] (ChIP Grade)
• Alternate name: ELAV-like protein 1, Human antigen R
• Research fields: Genetics
• Clone: 4C8
• Class: Monoclonal
• Conjugation: Unconjugated
• Reactivity: Human
• Host: Mouse
• Application: ChIP ; ELISA ; IHC ; EMSA
• Description: ELAV-like protein 1 or HuR (human antigen R) is a protein that in humans is encoded by the ELAVL1 gene. The protein encoded by this gene is a member of the ELAVL protein family. This encoded protein contains 3 RNA-binding domains and binds cis-acting AU-rich elements. It stabilizes mRNAs and thereby regulates gene expression. A popular technique is to use anti-HuR antibodies to pull out interacting mRNAs and thereby analyse gene expression in a particular tissue. Monoclonal antibody 4C8 was selected by its ability to bind to the HuR/mRNA complex and thus is very useful for EMSA, ChIP and CLIP studies.
• Immunogen: HuR peptide
• Isotype: IgG1

Target Details

• Target: HuR
• Target background: ELAV-like protein 1 or HuR (human antigen R) is a protein that in humans is encoded by the ELAVL1 gene. The protein encoded by this gene is a member of the ELAVL protein family. This encoded protein contains 3 RNA-binding domains and binds cis-acting AU-rich elements. It stabilizes mRNAs and thereby regulates gene expression. A popular technique is to use anti-HuR antibodies to pull out interacting mRNAs and thereby analyse gene expression in a particular tissue. Monoclonal antibody 4C8 was selected by its ability to bind to the HuR/mRNA complex and thus is very useful for EMSA, ChIP and CLIP studies.

Applications

• Application: ChIP ; ELISA ; IHC ; EMSA

Handling

• Format: Liquid
• Unit size: 100 ug
• Shipping conditions: Shipping at 4° C