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#152929

Anti-HLA DP alpha [TAL3C3]

Cat. #152929

Anti-HLA DP alpha [TAL3C3]

Cat. #: 152929

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 3-4 weeks

Target: HLA DP alpha (DQ to a lesser extent)

Class: Monoclonal

Application: IHC ; RIA ; WB

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Julia Bodmer

Institute: Cancer Research UK, London Research Institute: Lincoln's Inn Fields

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: Anti-HLA DP alpha [TAL3C3]
  • Research fields: Immunology
  • Clone: TAL3C3
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Molecular weight: 33 kDa
  • Strain: Balb/c
  • Reactivity: Human
  • Host: Mouse
  • Application: IHC ; RIA ; WB
  • Description: Human Leukocyte Antigens (HLA) are highly polymorphic proteins that are involved in the presentation of antigens to the T-cell receptor. There are two classes of HLA antigens, class I (HLA-A, HLA-B and HLA-C) and class II (HLA-D). TAL 3C3 may be used for tissue typing on lymphoblastoid cells, transplantation typing, disease susceptibility and detection of class II products.
  • Immunogen: Bristol 8 separated alpha chain preparation
  • Isotype: IgG1
  • Myeloma used: P3/NS1/1-Ag4-1

Target Details

  • Target: HLA DP alpha (DQ to a lesser extent)
  • Molecular weight: 33 kDa
  • Target background: Human Leukocyte Antigens (HLA) are highly polymorphic proteins that are involved in the presentation of antigens to the T-cell receptor. There are two classes of HLA antigens, class I (HLA-A, HLA-B and HLA-C) and class II (HLA-D). TAL 3C3 may be used for tissue typing on lymphoblastoid cells, transplantation typing, disease susceptibility and detection of class II products.

Applications

  • Application: IHC ; RIA ; WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Dry ice

References

  • Thomas et al. 1988. J Pathol. 154(4):353-63. PMID: 2455029.
  • HLA-D region alpha-chain monoclonal antibodies: cross-reaction between an anti-DP alpha-chain antibody and smooth muscle.
  • Adams et al. 1983. Immunology. 50(4):613-24. PMID: 6197354.
  • Production and characterization of monoclonal antibodies recognizing the alpha-chain subunits of human ia alloantigens.

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