Cat. #151078
Anti-HLA-B7 [BB7.1]
Cat. #: 151078
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-4 weeks
Target: HLA-B7
Class: Monoclonal
Application: FACS ; FACS
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Walter Bodmer
Institute: Cancer Research UK, London Research Institute: Lincoln's Inn Fields
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-HLA-B7 [BB7.1]
- Research fields: Immunology
- Clone: BB7.1
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Strain: Balb/c
- Reactivity: Human
- Host: Mouse
- Application: FACS ; FACS
- Description: This antibody can be used for HLA typing.
- Immunogen: Papain solubilised HLA-A2, B7
- Isotype: IgG1
- Myeloma used: P3/NS1/1-Ag4.1
Target Details
- Target: HLA-B7
- Target background: Human Leukocyte Antigens are highly polymorphic proteins that are involved in the presentation of antigens to the T-cell receptor. There are two classes of HLA antigens, class I (HLA-A, HLA-B and HLA-C) and class II (HLA-D).
Applications
- Application: FACS ; FACS
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Reches et al. 2016. J Immunol. :. PMID: 27194785.
- HNRNPR Regulates the Expression of Classical and Nonclassical MHC Class I Proteins.
- Dellgren et al. 2015. PLoS One. 10(8):e0135385. PMID: 26258424.
- Cell surface expression level variation between two common Human Leukocyte Antigen alleles, HLA-A2 and HLA-B8, is dependent on the structure of the C terminal part of the alpha 2 and the alpha 3 domains.
- Rancan et al. 2015. PLoS Pathog. 11(6):e1004906. PMID: 26067064.
- Latent Membrane Protein LMP2A Impairs Recognition of EBV-Infected Cells by CD8+ T Cells.
- Levering et al. 2000. Cytometry. 42(2):95-105. PMID: 10797446.
- External quality assessment of flow cytometric HLA-B27 typing.
- Parham et al. 1981. Hum Immunol. 3(4):277-99. PMID: 7035415.
- Partial purification and some properties of BB7.2. A cytotoxic monoclonal antibody with specificity for HLA-A2 and a variant of HLA-A28.
- Brodsky et al. 1979. Immunol Rev. 47:3-61. PMID: 95015.
- Monoclonal antibodies for analysis of the HLA system.
